Triple
T16852061
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | Harvoni |
E409697
|
entity |
| Predicate | hasTarget |
P14889
|
FINISHED |
| Object |
HCV NS5B RNA-dependent RNA polymerase
HCV NS5B RNA-dependent RNA polymerase is the viral enzyme in hepatitis C virus responsible for replicating its RNA genome and a key target for direct-acting antiviral drugs.
|
E1239451
|
NE FINISHED |
How this triple was built (4 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: HCV NS5B RNA-dependent RNA polymerase | Statement: [Harvoni, hasTarget, HCV NS5B RNA-dependent RNA polymerase]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: HCV NS5B RNA-dependent RNA polymerase Context triple: [Harvoni, hasTarget, HCV NS5B RNA-dependent RNA polymerase]
-
A.
HCV NS5A protein
HCV NS5A protein is a multifunctional nonstructural hepatitis C virus protein essential for viral RNA replication and assembly, and a key target of several direct-acting antiviral drugs.
-
B.
HIV-1 reverse transcriptase
HIV-1 reverse transcriptase is a viral enzyme that converts the HIV-1 RNA genome into DNA, making it a key target for antiretroviral drugs used in HIV treatment.
-
C.
HIV-1 integrase
HIV-1 integrase is a viral enzyme that inserts HIV-1’s genetic material into the host cell’s DNA, making it a key target for antiretroviral drugs.
-
D.
SARS-CoV-2 RNA-dependent RNA polymerase
SARS-CoV-2 RNA-dependent RNA polymerase is the key viral enzyme responsible for replicating the coronavirus’s RNA genome and is a primary target for antiviral drugs such as remdesivir.
-
E.
hepatitis C virus
Hepatitis C virus is a bloodborne RNA virus that primarily infects the liver, often causing chronic hepatitis, cirrhosis, and an increased risk of liver cancer.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg
Description generation
gpt-5.1
Instruction
Generate a one-sentence description of the target entity. You are given a context triple in the form (subject, predicate, object), where the object is the target entity. # Instructions Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. Avoid repeating the information from the triple, unless really essential. # Response Format Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: HCV NS5B RNA-dependent RNA polymerase Triple: [Harvoni, hasTarget, HCV NS5B RNA-dependent RNA polymerase]
Generated description
HCV NS5B RNA-dependent RNA polymerase is the viral enzyme in hepatitis C virus responsible for replicating its RNA genome and a key target for direct-acting antiviral drugs.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: HCV NS5B RNA-dependent RNA polymerase Target entity description: HCV NS5B RNA-dependent RNA polymerase is the viral enzyme in hepatitis C virus responsible for replicating its RNA genome and a key target for direct-acting antiviral drugs.
-
A.
HCV NS5A protein
HCV NS5A protein is a multifunctional nonstructural hepatitis C virus protein essential for viral RNA replication and assembly, and a key target of several direct-acting antiviral drugs.
-
B.
HIV-1 reverse transcriptase
HIV-1 reverse transcriptase is a viral enzyme that converts the HIV-1 RNA genome into DNA, making it a key target for antiretroviral drugs used in HIV treatment.
-
C.
HIV-1 integrase
HIV-1 integrase is a viral enzyme that inserts HIV-1’s genetic material into the host cell’s DNA, making it a key target for antiretroviral drugs.
-
D.
SARS-CoV-2 RNA-dependent RNA polymerase
SARS-CoV-2 RNA-dependent RNA polymerase is the key viral enzyme responsible for replicating the coronavirus’s RNA genome and is a primary target for antiviral drugs such as remdesivir.
-
E.
hepatitis C virus
Hepatitis C virus is a bloodborne RNA virus that primarily infects the liver, often causing chronic hepatitis, cirrhosis, and an increased risk of liver cancer.
- F. None of above. chosen
Provenance (5 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69d88395e6c88190b22730f335107c14 |
completed | April 10, 2026, 4:59 a.m. |
| NER | Named-entity recognition | batch_69e3b37abadc81909d02d329403497d6 |
completed | April 18, 2026, 4:38 p.m. |
| NED1 | Entity disambiguation (via context triple) | batch_6a00c7a08be48190bd2dbf83205c83ad |
completed | May 10, 2026, 6 p.m. |
| NEDg | Description generation | batch_6a00c84fd16c8190b9a7b50f1e77789c |
completed | May 10, 2026, 6:02 p.m. |
| NED2 | Entity disambiguation (via description) | batch_6a00c8bda3448190a1a5ba2af2b0e5d2 |
completed | May 10, 2026, 6:04 p.m. |
Created at: April 10, 2026, 5:24 a.m.