Triple

Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).

Phrase: Cram’s rule in stereochemistry | Statement: [Donald J. Cram, knownFor, Cram’s rule in stereochemistry]

Target entity: Cram’s rule in stereochemistry
Context triple: [Donald J. Cram, knownFor, Cram’s rule in stereochemistry]

• A. Theory of Orientation and Stereoselection
  Theory of Orientation and Stereoselection is a theoretical framework in organic chemistry that explains and predicts the regio- and stereochemical outcomes of reactions based on frontier molecular orbital interactions.
• B. Westheimer rules in physical organic chemistry
  Westheimer rules in physical organic chemistry are empirical guidelines that relate molecular structure and substituent effects to reaction rates and mechanisms, helping to rationalize and predict reactivity patterns.
• C. Woodward–Hoffmann rules
  The Woodward–Hoffmann rules are fundamental principles in organic chemistry that predict the stereochemistry and feasibility of pericyclic reactions based on orbital symmetry considerations.
• D. Enantioselective Chemical Synthesis
  Enantioselective Chemical Synthesis is a foundational work in organic chemistry that systematically presents strategies and methods for constructing chiral molecules with high stereocontrol.
• E. The Logic of Chemical Synthesis
  The Logic of Chemical Synthesis is a seminal book by chemist Elias J. Corey that systematically presents the principles and strategies of retrosynthetic analysis for designing complex organic molecule syntheses.
• F. None of above. chosen
• G. Unsure - the case is ambiguous/there is not enough information to decide.

Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"

Entity: Cram’s rule in stereochemistry
Triple: [Donald J. Cram, knownFor, Cram’s rule in stereochemistry]

Cram’s rule in stereochemistry is an empirical guideline that predicts the preferred stereochemical outcome of nucleophilic additions to carbonyl compounds adjacent to a chiral center.

Target entity: Cram’s rule in stereochemistry
Target entity description: Cram’s rule in stereochemistry is an empirical guideline that predicts the preferred stereochemical outcome of nucleophilic additions to carbonyl compounds adjacent to a chiral center.

• A. Theory of Orientation and Stereoselection
  Theory of Orientation and Stereoselection is a theoretical framework in organic chemistry that explains and predicts the regio- and stereochemical outcomes of reactions based on frontier molecular orbital interactions.
• B. Westheimer rules in physical organic chemistry
  Westheimer rules in physical organic chemistry are empirical guidelines that relate molecular structure and substituent effects to reaction rates and mechanisms, helping to rationalize and predict reactivity patterns.
• C. Woodward–Hoffmann rules
  The Woodward–Hoffmann rules are fundamental principles in organic chemistry that predict the stereochemistry and feasibility of pericyclic reactions based on orbital symmetry considerations.
• D. Enantioselective Chemical Synthesis
  Enantioselective Chemical Synthesis is a foundational work in organic chemistry that systematically presents strategies and methods for constructing chiral molecules with high stereocontrol.
• E. The Logic of Chemical Synthesis
  The Logic of Chemical Synthesis is a seminal book by chemist Elias J. Corey that systematically presents the principles and strategies of retrosynthetic analysis for designing complex organic molecule syntheses.
• F. None of above. chosen