Triple
T15983058
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | Juno Therapeutics |
E387620
|
entity |
| Predicate | therapeuticTarget |
P37016
|
FINISHED |
| Object |
CD19
CD19 is a B-cell surface protein widely used as a key immunotherapy target in treatments for B-cell malignancies such as certain leukemias and lymphomas.
|
E1188119
|
NE FINISHED |
How this triple was built (5 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: CD19 | Statement: [Juno Therapeutics, therapeuticTarget, CD19]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: CD19 Context triple: [Juno Therapeutics, therapeuticTarget, CD19]
-
A.
CD22
CD22 is a B-cell–specific surface glycoprotein that functions as an inhibitory co-receptor modulating B cell receptor signaling and immune responses.
-
B.
CD21
CD21 is a complement receptor (CR2) found on B cells and follicular dendritic cells that plays a key role in B cell activation and the immune response.
-
C.
CD20 protein
CD20 protein is a cell-surface antigen found primarily on B lymphocytes and is a key therapeutic target in certain autoimmune diseases and B-cell malignancies.
-
D.
CD46
CD46 is a human cell-surface complement regulatory protein that also serves as an entry receptor for various pathogens, including certain adenoviruses and measles virus.
-
E.
CD38
CD38 is a cell surface glycoprotein with ectoenzyme and receptor functions, highly expressed on plasma cells and targeted in therapies for multiple myeloma and other hematologic malignancies.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg
Description generation
gpt-5.1
Instruction
Generate a one-sentence description of the target entity. You are given a context triple in the form (subject, predicate, object), where the object is the target entity. # Instructions Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. Avoid repeating the information from the triple, unless really essential. # Response Format Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: CD19 Triple: [Juno Therapeutics, therapeuticTarget, CD19]
Generated description
CD19 is a B-cell surface protein widely used as a key immunotherapy target in treatments for B-cell malignancies such as certain leukemias and lymphomas.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: CD19 Target entity description: CD19 is a B-cell surface protein widely used as a key immunotherapy target in treatments for B-cell malignancies such as certain leukemias and lymphomas.
-
A.
CD22
CD22 is a B-cell–specific surface glycoprotein that functions as an inhibitory co-receptor modulating B cell receptor signaling and immune responses.
-
B.
CD21
CD21 is a complement receptor (CR2) found on B cells and follicular dendritic cells that plays a key role in B cell activation and the immune response.
-
C.
CD20 protein
CD20 protein is a cell-surface antigen found primarily on B lymphocytes and is a key therapeutic target in certain autoimmune diseases and B-cell malignancies.
-
D.
CD46
CD46 is a human cell-surface complement regulatory protein that also serves as an entry receptor for various pathogens, including certain adenoviruses and measles virus.
-
E.
CD38
CD38 is a cell surface glycoprotein with ectoenzyme and receptor functions, highly expressed on plasma cells and targeted in therapies for multiple myeloma and other hematologic malignancies.
- F. None of above. chosen
PD
Predicate disambiguation
gpt-5-mini-2025-08-07
Target predicate: therapeuticTarget Context triple: [Juno Therapeutics, therapeuticTarget, CD19]
-
A.
regulatoryTarget
Indicates that one entity is subject to control, influence, or governance by another entity under a regulatory or rule-based framework.
-
B.
hasMolecularTarget
chosen
Indicates that one entity (such as a drug or compound) is directed toward, binds to, or specifically interacts with a particular molecular target (such as a protein, receptor, or gene).
-
C.
hasTherapeuticGoal
Indicates that an action, treatment, or intervention is undertaken with the intention of achieving a specific therapeutic or health-related outcome.
-
D.
potentialTherapeuticUse
Indicates that something is being considered or investigated as a possible treatment or therapy for a condition or disease.
-
E.
hasTargetDisease
Indicates that an entity (such as a treatment, study, or intervention) is directed toward, intended to affect, or primarily concerned with a specified disease.
- F. None of above.
Provenance (6 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69d86da94ccc819083d187f5dc6a123e |
completed | April 10, 2026, 3:25 a.m. |
| NER | Named-entity recognition | batch_69e17d4d08f481909f38b75e3f42d9ab |
completed | April 17, 2026, 12:22 a.m. |
| NED1 | Entity disambiguation (via context triple) | batch_69ffc3cdf7848190848e9081027dc027 |
completed | May 9, 2026, 11:31 p.m. |
| NEDg | Description generation | batch_69ffc5669c1c81909bacf61c96cb7816 |
completed | May 9, 2026, 11:38 p.m. |
| NED2 | Entity disambiguation (via description) | batch_69ffc5c7db1c8190b4e1de6f6e3ce8a0 |
completed | May 9, 2026, 11:39 p.m. |
| PD | Predicate disambiguation | batch_69e142d9d8e881909b559a3e3ca21d24 |
completed | April 16, 2026, 8:13 p.m. |
Created at: April 10, 2026, 4:54 a.m.