Triple

T15983058
Position Surface form Disambiguated ID Type / Status
Subject Juno Therapeutics E387620 entity
Predicate therapeuticTarget P37016 FINISHED
Object CD19
CD19 is a B-cell surface protein widely used as a key immunotherapy target in treatments for B-cell malignancies such as certain leukemias and lymphomas.
E1188119 NE FINISHED

How this triple was built (5 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: CD19 | Statement: [Juno Therapeutics, therapeuticTarget, CD19]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: CD19
Context triple: [Juno Therapeutics, therapeuticTarget, CD19]
  • A. CD22
    CD22 is a B-cell–specific surface glycoprotein that functions as an inhibitory co-receptor modulating B cell receptor signaling and immune responses.
  • B. CD21
    CD21 is a complement receptor (CR2) found on B cells and follicular dendritic cells that plays a key role in B cell activation and the immune response.
  • C. CD20 protein
    CD20 protein is a cell-surface antigen found primarily on B lymphocytes and is a key therapeutic target in certain autoimmune diseases and B-cell malignancies.
  • D. CD46
    CD46 is a human cell-surface complement regulatory protein that also serves as an entry receptor for various pathogens, including certain adenoviruses and measles virus.
  • E. CD38
    CD38 is a cell surface glycoprotein with ectoenzyme and receptor functions, highly expressed on plasma cells and targeted in therapies for multiple myeloma and other hematologic malignancies.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: CD19
Triple: [Juno Therapeutics, therapeuticTarget, CD19]
Generated description
CD19 is a B-cell surface protein widely used as a key immunotherapy target in treatments for B-cell malignancies such as certain leukemias and lymphomas.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: CD19
Target entity description: CD19 is a B-cell surface protein widely used as a key immunotherapy target in treatments for B-cell malignancies such as certain leukemias and lymphomas.
  • A. CD22
    CD22 is a B-cell–specific surface glycoprotein that functions as an inhibitory co-receptor modulating B cell receptor signaling and immune responses.
  • B. CD21
    CD21 is a complement receptor (CR2) found on B cells and follicular dendritic cells that plays a key role in B cell activation and the immune response.
  • C. CD20 protein
    CD20 protein is a cell-surface antigen found primarily on B lymphocytes and is a key therapeutic target in certain autoimmune diseases and B-cell malignancies.
  • D. CD46
    CD46 is a human cell-surface complement regulatory protein that also serves as an entry receptor for various pathogens, including certain adenoviruses and measles virus.
  • E. CD38
    CD38 is a cell surface glycoprotein with ectoenzyme and receptor functions, highly expressed on plasma cells and targeted in therapies for multiple myeloma and other hematologic malignancies.
  • F. None of above. chosen
PD Predicate disambiguation gpt-5-mini-2025-08-07
Target predicate: therapeuticTarget
Context triple: [Juno Therapeutics, therapeuticTarget, CD19]
  • A. regulatoryTarget
    Indicates that one entity is subject to control, influence, or governance by another entity under a regulatory or rule-based framework.
  • B. hasMolecularTarget chosen
    Indicates that one entity (such as a drug or compound) is directed toward, binds to, or specifically interacts with a particular molecular target (such as a protein, receptor, or gene).
  • C. hasTherapeuticGoal
    Indicates that an action, treatment, or intervention is undertaken with the intention of achieving a specific therapeutic or health-related outcome.
  • D. potentialTherapeuticUse
    Indicates that something is being considered or investigated as a possible treatment or therapy for a condition or disease.
  • E. hasTargetDisease
    Indicates that an entity (such as a treatment, study, or intervention) is directed toward, intended to affect, or primarily concerned with a specified disease.
  • F. None of above.

Provenance (6 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69d86da94ccc819083d187f5dc6a123e completed April 10, 2026, 3:25 a.m.
NER Named-entity recognition batch_69e17d4d08f481909f38b75e3f42d9ab completed April 17, 2026, 12:22 a.m.
NED1 Entity disambiguation (via context triple) batch_69ffc3cdf7848190848e9081027dc027 completed May 9, 2026, 11:31 p.m.
NEDg Description generation batch_69ffc5669c1c81909bacf61c96cb7816 completed May 9, 2026, 11:38 p.m.
NED2 Entity disambiguation (via description) batch_69ffc5c7db1c8190b4e1de6f6e3ce8a0 completed May 9, 2026, 11:39 p.m.
PD Predicate disambiguation batch_69e142d9d8e881909b559a3e3ca21d24 completed April 16, 2026, 8:13 p.m.
Created at: April 10, 2026, 4:54 a.m.