Triple

T15982894
Position Surface form Disambiguated ID Type / Status
Subject Vertex Pharmaceuticals E387617 entity
Predicate brandName P1500 FINISHED
Object Orkambi
Orkambi is a prescription combination therapy (lumacaftor/ivacaftor) used to treat cystic fibrosis in patients with specific CFTR gene mutations.
E1188102 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: Orkambi | Statement: [Vertex Pharmaceuticals, brandName, Orkambi]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: Orkambi
Context triple: [Vertex Pharmaceuticals, brandName, Orkambi]
  • A. Oribos
    Oribos is the central hub city and afterlife crossroads in World of Warcraft: Shadowlands, where players gather, trade, and access the expansion’s various realms.
  • B. Orbiana
    Orbiana was a Roman empress of the 3rd century, briefly married to Emperor Severus Alexander before falling victim to court intrigues that led to her exile.
  • C. Orbiel
    The Orbiel is a river in southern France that flows through the Aude department before joining the Aude River.
  • D. Oukaimeden
    Oukaimeden is a popular ski resort and mountain destination in the High Atlas Mountains of Morocco, known for its winter sports and scenic alpine landscapes.
  • E. Yvorne
    Yvorne is a small municipality in the canton of Vaud in western Switzerland, known for its vineyards and scenic Alpine surroundings.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: Orkambi
Triple: [Vertex Pharmaceuticals, brandName, Orkambi]
Generated description
Orkambi is a prescription combination therapy (lumacaftor/ivacaftor) used to treat cystic fibrosis in patients with specific CFTR gene mutations.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: Orkambi
Target entity description: Orkambi is a prescription combination therapy (lumacaftor/ivacaftor) used to treat cystic fibrosis in patients with specific CFTR gene mutations.
  • A. Oribos
    Oribos is the central hub city and afterlife crossroads in World of Warcraft: Shadowlands, where players gather, trade, and access the expansion’s various realms.
  • B. Orbiana
    Orbiana was a Roman empress of the 3rd century, briefly married to Emperor Severus Alexander before falling victim to court intrigues that led to her exile.
  • C. Orbiel
    The Orbiel is a river in southern France that flows through the Aude department before joining the Aude River.
  • D. Oukaimeden
    Oukaimeden is a popular ski resort and mountain destination in the High Atlas Mountains of Morocco, known for its winter sports and scenic alpine landscapes.
  • E. Yvorne
    Yvorne is a small municipality in the canton of Vaud in western Switzerland, known for its vineyards and scenic Alpine surroundings.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69d86da94ccc819083d187f5dc6a123e completed April 10, 2026, 3:25 a.m.
NER Named-entity recognition batch_69e15755b5548190acfa29eecb11e675 completed April 16, 2026, 9:40 p.m.
NED1 Entity disambiguation (via context triple) batch_69ffc3cdf7848190848e9081027dc027 completed May 9, 2026, 11:31 p.m.
NEDg Description generation batch_69ffc5669c1c81909bacf61c96cb7816 completed May 9, 2026, 11:38 p.m.
NED2 Entity disambiguation (via description) batch_69ffc5c7db1c8190b4e1de6f6e3ce8a0 completed May 9, 2026, 11:39 p.m.
Created at: April 10, 2026, 4:54 a.m.