Triple
T11074718
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | Docetaxel |
E261833
|
entity |
| Predicate | primaryMetabolismEnzyme |
P37221
|
FINISHED |
| Object | CYP3A4 |
E242412
|
NE FINISHED |
How this triple was built (3 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: CYP3A4 | Statement: [Docetaxel, primaryMetabolismEnzyme, CYP3A4]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: CYP3A4 Context triple: [Docetaxel, primaryMetabolismEnzyme, CYP3A4]
-
A.
CYP3A4
chosen
CYP3A4 is a major human liver and intestinal enzyme of the cytochrome P450 family responsible for metabolizing a wide range of drugs and xenobiotics.
-
B.
CYP2B6
CYP2B6 is a human liver cytochrome P450 enzyme that plays a key role in the metabolism of various drugs and xenobiotics.
-
C.
CYP1A2
CYP1A2 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs and xenobiotics.
-
D.
CYP2C19
CYP2C19 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs, including certain antidepressants, proton pump inhibitors, and antiplatelet agents.
-
E.
CYP2C9
CYP2C9 is a liver enzyme of the cytochrome P450 family that plays a key role in metabolizing various drugs, including many nonsteroidal anti-inflammatory agents and anticoagulants.
- F. None of above.
- G. Unsure - the case is ambiguous/there is not enough information to decide.
PD
Predicate disambiguation
gpt-5-mini-2025-08-07
Target predicate: primaryMetabolismEnzyme Context triple: [Docetaxel, primaryMetabolismEnzyme, CYP3A4]
-
A.
primaryMetabolite
Indicates that one entity is a primary metabolite, i.e., a small molecule directly involved in essential cellular metabolic processes.
-
B.
isMetabolizedBy
chosen
Indicates that a substance is biochemically broken down or transformed through metabolic processes carried out by a specified organism, cell type, or enzyme system.
-
C.
metabolismType
Indicates the kind of metabolic process or pathway an entity uses to obtain and transform energy or nutrients.
-
D.
secondaryMetabolite
Indicates that one entity is a secondary metabolite produced by, associated with, or derived from another entity (such as an organism, pathway, or gene).
-
E.
isMetabolizedPrimarilyIn
Indicates that the substance undergoes its main metabolic processing within the specified biological system or organ.
- F. None of above.
Provenance (4 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69d6aa9983c08190b0ef61603b69feac |
completed | April 8, 2026, 7:20 p.m. |
| NER | Named-entity recognition | batch_69d7994efb608190a81bc8c4d16ddbd0 |
completed | April 9, 2026, 12:19 p.m. |
| NED1 | Entity disambiguation (via context triple) | batch_69e3e77a78288190aa76912e0fa821b5 |
completed | April 18, 2026, 8:20 p.m. |
| PD | Predicate disambiguation | batch_69d74415403c81909778bcd829e8832e |
completed | April 9, 2026, 6:15 a.m. |
Created at: April 8, 2026, 9:26 p.m.