Triple
T11074233
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | HER2 receptor |
E261824
|
entity |
| Predicate | formsHeterodimerWith |
P6653
|
FINISHED |
| Object |
EGFR
EGFR (epidermal growth factor receptor) is a transmembrane receptor tyrosine kinase that regulates cell growth and survival and is frequently implicated in cancer development and progression.
|
E902872
|
NE FINISHED |
How this triple was built (5 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: EGFR | Statement: [HER2 receptor, formsHeterodimerWith, EGFR]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: EGFR Context triple: [HER2 receptor, formsHeterodimerWith, EGFR]
-
A.
ERBB2
ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
-
B.
EGF
EGF is the ICAO airline designator used to identify American Eagle Airlines in aviation operations and communications.
-
C.
HER2 receptor
The HER2 receptor is a cell surface protein and member of the epidermal growth factor receptor family that, when overexpressed, drives the growth of certain aggressive breast and other cancers.
-
D.
EWSR1
EWSR1 is a multifunctional RNA-binding protein involved in transcriptional regulation and RNA processing, best known for its role in chromosomal translocations that drive various sarcomas and leukemias.
-
E.
CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg
Description generation
gpt-5.1
Instruction
Generate a one-sentence description of the target entity. You are given a context triple in the form (subject, predicate, object), where the object is the target entity. # Instructions Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. Avoid repeating the information from the triple, unless really essential. # Response Format Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: EGFR Triple: [HER2 receptor, formsHeterodimerWith, EGFR]
Generated description
EGFR (epidermal growth factor receptor) is a transmembrane receptor tyrosine kinase that regulates cell growth and survival and is frequently implicated in cancer development and progression.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: EGFR Target entity description: EGFR (epidermal growth factor receptor) is a transmembrane receptor tyrosine kinase that regulates cell growth and survival and is frequently implicated in cancer development and progression.
-
A.
ERBB2
ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
-
B.
EGF
EGF is the ICAO airline designator used to identify American Eagle Airlines in aviation operations and communications.
-
C.
HER2 receptor
The HER2 receptor is a cell surface protein and member of the epidermal growth factor receptor family that, when overexpressed, drives the growth of certain aggressive breast and other cancers.
-
D.
EWSR1
EWSR1 is a multifunctional RNA-binding protein involved in transcriptional regulation and RNA processing, best known for its role in chromosomal translocations that drive various sarcomas and leukemias.
-
E.
CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
- F. None of above. chosen
PD
Predicate disambiguation
gpt-5-mini-2025-08-07
Target predicate: formsHeterodimerWith Context triple: [HER2 receptor, formsHeterodimerWith, EGFR]
-
A.
formsWeakDoubletWith
Indicates that one entity forms a weakly interacting or loosely coupled pair (doublet) with another entity, typically in contrast to a stronger or more tightly bound association.
-
B.
formedDuoWith
Indicates that two entities joined together to create a duo, typically collaborating or acting as a pair for a shared purpose or activity.
-
C.
formsWith
chosen
Indicates that one entity combines or associates with another to create or constitute a joint structure, group, or configuration.
-
D.
homologousTo
Indicates that two entities share a common evolutionary origin or structural similarity, often implying they derive from the same ancestral feature.
-
E.
formedAsPartnershipBetween
Indicates that something was created or established through a formal partnership between two or more entities.
- F. None of above.
Provenance (6 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69d6aa9983c08190b0ef61603b69feac |
completed | April 8, 2026, 7:20 p.m. |
| NER | Named-entity recognition | batch_69d7994e32fc8190a6591d9e82b68f75 |
completed | April 9, 2026, 12:19 p.m. |
| NED1 | Entity disambiguation (via context triple) | batch_69e3c8cc77988190aad54f56dbd0f8cf |
completed | April 18, 2026, 6:09 p.m. |
| NEDg | Description generation | batch_69e3cefc00148190a1850dc6e31523c3 |
completed | April 18, 2026, 6:35 p.m. |
| NED2 | Entity disambiguation (via description) | batch_69e3d014a644819092c76aa02b573ca9 |
completed | April 18, 2026, 6:40 p.m. |
| PD | Predicate disambiguation | batch_69d74415403c81909778bcd829e8832e |
completed | April 9, 2026, 6:15 a.m. |
Created at: April 8, 2026, 9:26 p.m.