Triple

T10292249
Position Surface form Disambiguated ID Type / Status
Subject Genmab E241390 entity
Predicate product P490 FINISHED
Object Teprotumumab
Teprotumumab is a monoclonal antibody drug used primarily to treat thyroid eye disease by targeting the insulin-like growth factor-1 receptor (IGF-1R).
E854987 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: Teprotumumab | Statement: [Genmab, product, Teprotumumab]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: Teprotumumab
Context triple: [Genmab, product, Teprotumumab]
  • A. Onpattro
    Onpattro is an RNA interference (RNAi) therapeutic used to treat polyneuropathy in adults with hereditary transthyretin-mediated (hATTR) amyloidosis.
  • B. Vitrakvi
    Vitrakvi is a targeted cancer therapy (larotrectinib) used to treat solid tumors that have a specific NTRK gene fusion, regardless of the tumor’s location in the body.
  • C. Zaltrap
    Zaltrap is a cancer medication (brand name for aflibercept) used primarily in combination chemotherapy to treat metastatic colorectal cancer by inhibiting vascular endothelial growth factor (VEGF).
  • D. aflibercept
    Aflibercept is an anti-VEGF biologic drug used primarily to treat neovascular (wet) age-related macular degeneration and other retinal vascular diseases.
  • E. Alimta
    Alimta is a chemotherapy drug (pemetrexed) primarily used to treat malignant pleural mesothelioma and non-small cell lung cancer.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: Teprotumumab
Triple: [Genmab, product, Teprotumumab]
Generated description
Teprotumumab is a monoclonal antibody drug used primarily to treat thyroid eye disease by targeting the insulin-like growth factor-1 receptor (IGF-1R).
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: Teprotumumab
Target entity description: Teprotumumab is a monoclonal antibody drug used primarily to treat thyroid eye disease by targeting the insulin-like growth factor-1 receptor (IGF-1R).
  • A. Onpattro
    Onpattro is an RNA interference (RNAi) therapeutic used to treat polyneuropathy in adults with hereditary transthyretin-mediated (hATTR) amyloidosis.
  • B. Vitrakvi
    Vitrakvi is a targeted cancer therapy (larotrectinib) used to treat solid tumors that have a specific NTRK gene fusion, regardless of the tumor’s location in the body.
  • C. Zaltrap
    Zaltrap is a cancer medication (brand name for aflibercept) used primarily in combination chemotherapy to treat metastatic colorectal cancer by inhibiting vascular endothelial growth factor (VEGF).
  • D. aflibercept
    Aflibercept is an anti-VEGF biologic drug used primarily to treat neovascular (wet) age-related macular degeneration and other retinal vascular diseases.
  • E. Alimta
    Alimta is a chemotherapy drug (pemetrexed) primarily used to treat malignant pleural mesothelioma and non-small cell lung cancer.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69d381aaafc08190af475ef58dc16aba completed April 6, 2026, 9:49 a.m.
NER Named-entity recognition batch_69d4d2d35f048190a215493acdf1f718 completed April 7, 2026, 9:48 a.m.
NED1 Entity disambiguation (via context triple) batch_69d71d1465e88190aaa8b295df3f9c8c completed April 9, 2026, 3:29 a.m.
NEDg Description generation batch_69d73180d90481908f1b4768230edd36 completed April 9, 2026, 4:56 a.m.
NED2 Entity disambiguation (via description) batch_69d7326b14988190bff33dc01e690707 completed April 9, 2026, 5 a.m.
Created at: April 6, 2026, 11:42 a.m.