Triple

T10292210
Position Surface form Disambiguated ID Type / Status
Subject thalidomide E241389 entity
Predicate riskManagementProgramName P92927 FINISHED
Object Thalomid REMS
Thalomid REMS is a specialized U.S. risk evaluation and mitigation strategy program designed to tightly control the prescribing and dispensing of thalidomide due to its severe teratogenic and safety risks.
E647147 NE FINISHED

How this triple was built (5 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: Thalomid REMS | Statement: [thalidomide, riskManagementProgramName, Thalomid REMS]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: Thalomid REMS
Context triple: [thalidomide, riskManagementProgramName, Thalomid REMS]
  • A. thalidomide
    Thalidomide is an immunomodulatory drug historically known for causing severe birth defects, now used under strict controls to treat conditions such as multiple myeloma and complications of leprosy.
  • B. Tasigna
    Tasigna is a prescription tyrosine kinase inhibitor used primarily to treat certain types of Philadelphia chromosome–positive chronic myeloid leukemia (CML) in adults and children.
  • C. FDA Risk Evaluation and Mitigation Strategies authority
    The FDA Risk Evaluation and Mitigation Strategies authority is the U.S. Food and Drug Administration’s power to require special safety measures and monitoring programs for certain high-risk prescription drugs to ensure their benefits outweigh their risks.
  • D. Inflectra
    Inflectra is a biosimilar monoclonal antibody to infliximab used to treat autoimmune inflammatory conditions such as rheumatoid arthritis, Crohn’s disease, and ulcerative colitis.
  • E. Biktarvy
    Biktarvy is a prescription combination antiretroviral medication used to treat HIV-1 infection in adults and certain children.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: Thalomid REMS
Triple: [thalidomide, riskManagementProgramName, Thalomid REMS]
Generated description
Thalomid REMS is a specialized U.S. risk evaluation and mitigation strategy program designed to tightly control the prescribing and dispensing of thalidomide due to its severe teratogenic and safety risks.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: Thalomid REMS
Target entity description: Thalomid REMS is a specialized U.S. risk evaluation and mitigation strategy program designed to tightly control the prescribing and dispensing of thalidomide due to its severe teratogenic and safety risks.
  • A. thalidomide
    Thalidomide is an immunomodulatory drug historically known for causing severe birth defects, now used under strict controls to treat conditions such as multiple myeloma and complications of leprosy.
  • B. Tasigna
    Tasigna is a prescription tyrosine kinase inhibitor used primarily to treat certain types of Philadelphia chromosome–positive chronic myeloid leukemia (CML) in adults and children.
  • C. FDA Risk Evaluation and Mitigation Strategies authority chosen
    The FDA Risk Evaluation and Mitigation Strategies authority is the U.S. Food and Drug Administration’s power to require special safety measures and monitoring programs for certain high-risk prescription drugs to ensure their benefits outweigh their risks.
  • D. Inflectra
    Inflectra is a biosimilar monoclonal antibody to infliximab used to treat autoimmune inflammatory conditions such as rheumatoid arthritis, Crohn’s disease, and ulcerative colitis.
  • E. Biktarvy
    Biktarvy is a prescription combination antiretroviral medication used to treat HIV-1 infection in adults and certain children.
  • F. None of above.
PD Predicate disambiguation gpt-5-mini-2025-08-07
Target predicate: riskManagementProgramName
Context triple: [thalidomide, riskManagementProgramName, Thalomid REMS]
  • A. riskManagement
    Indicates the implementation of strategies and actions to identify, assess, and mitigate potential risks associated with an entity or activity.
  • B. riskManagementMechanism
    Indicates a mechanism, process, or control used to identify, assess, mitigate, or monitor risks associated with an entity or activity.
  • C. riskManagedBy
    Indicates that the potential or identified risk is controlled, mitigated, or overseen through the actions, policies, or responsibilities of a specified managing entity.
  • D. riskManagementGoal
    Indicates the objective or desired outcome that guides how risks are identified, assessed, and controlled within a risk management process.
  • E. safetyPrograms
    Indicates that there are organized measures, policies, or initiatives implemented to protect people or assets from harm or risk.
  • F. None of above. chosen

Provenance (7 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69d381aaafc08190af475ef58dc16aba completed April 6, 2026, 9:49 a.m.
NER Named-entity recognition batch_69d4d2d35f048190a215493acdf1f718 completed April 7, 2026, 9:48 a.m.
NED1 Entity disambiguation (via context triple) batch_69d71d1465e88190aaa8b295df3f9c8c completed April 9, 2026, 3:29 a.m.
NEDg Description generation batch_69d73180d90481908f1b4768230edd36 completed April 9, 2026, 4:56 a.m.
NED2 Entity disambiguation (via description) batch_69d7326b14988190bff33dc01e690707 completed April 9, 2026, 5 a.m.
PD Predicate disambiguation batch_69d4d1f35e548190be3b4d92d65d2d20 completed April 7, 2026, 9:44 a.m.
PDg Predicate description generation batch_69d4d29d7cf08190acd70cee634c5cdb completed April 7, 2026, 9:47 a.m.
Created at: April 6, 2026, 11:42 a.m.