Triple
T10292121
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | bortezomib |
E241388
|
entity |
| Predicate | instanceOf |
P0
|
FINISHED |
| Object | proteasome inhibitor |
C27667
|
CONCEPT FINISHED |
How this triple was built (1 step)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
CD
Concept disambiguation
gpt-5-mini-2025-08-07
Target class: proteasome inhibitor Context triple: [bortezomib, instanceOf, proteasome inhibitor]
-
A.
CDK4/6 inhibitor
A CDK4/6 inhibitor is a targeted anticancer drug that blocks cyclin-dependent kinases 4 and 6 to halt cell cycle progression from G1 to S phase, thereby inhibiting tumor cell proliferation.
-
B.
Bruton tyrosine kinase inhibitor
A Bruton tyrosine kinase inhibitor is a targeted small-molecule drug that blocks BTK signaling in B cells to disrupt pathways critical for their activation, proliferation, and survival, primarily used in the treatment of certain B-cell malignancies and autoimmune diseases.
-
C.
angiogenesis inhibitor
An angiogenesis inhibitor is an agent that blocks the formation of new blood vessels, typically to restrict blood supply to tumors or abnormal tissues.
-
D.
antimetabolite
An antimetabolite is a drug that mimics natural cellular metabolites to interfere with DNA or RNA synthesis, thereby inhibiting cell growth and division, commonly used in cancer and autoimmune disease treatment.
-
E.
cytochrome P450 enzyme
A cytochrome P450 enzyme is a heme-containing monooxygenase that catalyzes the oxidation of a wide variety of endogenous and exogenous substrates, playing key roles in metabolism, detoxification, and biosynthesis.
- F. None of above. chosen
Provenance (1 batch)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69d381aaafc08190af475ef58dc16aba |
completed | April 6, 2026, 9:49 a.m. |
Created at: April 6, 2026, 11:42 a.m.