Kinyoun stain

E929611

Kinyoun stain is a cold acid-fast staining technique used in microbiology as a safer, non-heated alternative to the Ziehl–Neelsen method for detecting organisms like Mycobacterium species.

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Statements (47)

Predicate Object
instanceOf acid-fast staining technique
laboratory technique
microbiological staining method
advantage avoids production of potentially infectious aerosols from heating
safer than heated Ziehl–Neelsen method
simpler equipment requirements
alsoKnownAs Kinyoun method NERFINISHED
cold acid-fast stain
appliedTo clinical specimens
sputum smears
tissue sections
basedOn Ziehl–Neelsen stain NERFINISHED
comparedTo Ziehl–Neelsen stain NERFINISHED
developedBy Joseph J. Kinyoun NERFINISHED
field medical microbiology
microbiology
hasCharacteristic carbol fuchsin primary stain
cold method
does not require heating to drive stain into cells
high concentration of basic fuchsin
high concentration of phenol
non-heated method
retains primary stain in acid-fast organisms after decolorization
relatedTo Auramine–rhodamine stain
Ziehl–Neelsen stain NERFINISHED
fluorochrome acid-fast stain
requiresStep application of primary stain
counterstaining
decolorization with acid-alcohol
safetyConsideration avoids open flame heating of slides
phenol is toxic and requires ventilation
usedFor detection of Mycobacterium species
detection of Mycobacterium tuberculosis
detection of Nocardia species
detection of acid-fast bacteria
detection of partially acid-fast organisms
usedIn clinical microbiology laboratories
diagnosis of mycobacterial infections
diagnosis of tuberculosis
usesReagent acid-alcohol decolorizer
brilliant green counterstain
carbol fuchsin
methylene blue counterstain
phenol
sulfuric acid decolorizer
visualizes blue background with methylene blue counterstain
red acid-fast bacilli

Referenced by (1)

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Ziehl–Neelsen stain contrastWith Kinyoun stain