Corynebacterium diphtheriae
E928055
Corynebacterium diphtheriae is a Gram-positive, toxin-producing bacterium that causes the infectious disease diphtheria in humans.
Statements (52)
| Predicate | Object |
|---|---|
| instanceOf |
bacterial species
ⓘ
pathogenic bacterium ⓘ |
| arrangement |
Chinese-letter pattern
ⓘ
palisades ⓘ |
| catalaseActivity | catalase-positive ⓘ |
| causes | diphtheria ⓘ |
| cellMorphology | club-shaped rods ⓘ |
| cellWallComponent | mycolic acids ⓘ |
| class | Actinobacteria NERFINISHED ⓘ |
| clinicalManifestation |
bull neck
ⓘ
pseudomembrane formation in throat ⓘ |
| complication |
airway obstruction
ⓘ
myocarditis ⓘ peripheral neuropathy ⓘ |
| cultureMedium |
Loeffler medium
ⓘ
potassium tellurite agar ⓘ |
| diagnosticTest |
Elek test
NERFINISHED
ⓘ
PCR for tox gene ⓘ |
| domain | Bacteria ⓘ |
| family | Corynebacteriaceae NERFINISHED ⓘ |
| firstDescribedBy | Edwin Klebs NERFINISHED ⓘ |
| genus | Corynebacterium NERFINISHED ⓘ |
| gramStain | Gram-positive ⓘ |
| host | humans ⓘ |
| motility | non-motile ⓘ |
| order | Corynebacteriales NERFINISHED ⓘ |
| oxygenRequirement | facultative anaerobe ⓘ |
| pathogenesisMechanism | inhibition of host protein synthesis ⓘ |
| phylum | Actinobacteriota NERFINISHED ⓘ |
| preventedBy |
DTP vaccine
NERFINISHED
ⓘ
DTaP vaccine NERFINISHED ⓘ Tdap vaccine NERFINISHED ⓘ |
| primaryInfectionSite |
pharynx
ⓘ
tonsils ⓘ upper respiratory tract ⓘ |
| shape | rod-shaped ⓘ |
| sporeFormation | non-spore-forming ⓘ |
| stain |
Albert stain
NERFINISHED
ⓘ
Neisser stain NERFINISHED ⓘ |
| stainingCharacteristic | metachromatic granules ⓘ |
| targetMolecule | elongation factor 2 ⓘ |
| taxonRank | species ⓘ |
| toxinActivity | ADP-ribosylation of EF-2 ⓘ |
| toxinGene | tox gene ⓘ |
| toxinGeneLocation | lysogenic bacteriophage ⓘ |
| toxinType | A-B exotoxin ⓘ |
| transmissionRoute |
close person-to-person contact
ⓘ
contaminated fomites ⓘ respiratory droplets ⓘ |
| vaccineTarget | diphtheria toxoid ⓘ |
| virulenceFactor | diphtheria toxin ⓘ |
| yearDescribed | 1884 ⓘ |
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.