Mycobacterium leprae
E928041
Mycobacterium leprae is a slow-growing, acid-fast bacterium that causes leprosy (Hansen’s disease) in humans.
Statements (51)
| Predicate | Object |
|---|---|
| instanceOf |
acid-fast bacterium
ⓘ
bacterium ⓘ pathogen ⓘ |
| acidFastComponent | mycolic acids ⓘ |
| antimicrobialSusceptibility |
clofazimine-sensitive
ⓘ
dapsone-sensitive ⓘ rifampicin-sensitive ⓘ |
| cellEnvelopeComponent | phenolic glycolipid-1 ⓘ |
| cellWallProperty | acid-fast ⓘ |
| clinicalAssociation |
borderline forms of leprosy
ⓘ
lepromatous leprosy ⓘ tuberculoid leprosy ⓘ |
| cultureProperty |
can be propagated in armadillo
ⓘ
can be propagated in mouse footpad ⓘ not cultivable on standard artificial media ⓘ |
| discoveredBy | Gerhard Armauer Hansen NERFINISHED ⓘ |
| diseaseCaused |
Hansen’s disease
ⓘ
leprosy ⓘ |
| domain | Bacteria NERFINISHED ⓘ |
| doublingTime | about 12 to 14 days ⓘ |
| family | Mycobacteriaceae NERFINISHED ⓘ |
| genomeFeature |
high proportion of pseudogenes
ⓘ
reductive evolution ⓘ |
| genomeSize | approximately 3.3 Mb ⓘ |
| genomeType |
circular chromosome
ⓘ
double-stranded DNA ⓘ |
| genus | Mycobacterium NERFINISHED ⓘ |
| gramStain | Gram-positive ⓘ |
| growthRate | slow-growing ⓘ |
| immuneEvasionMechanism |
modulation of cell-mediated immunity
ⓘ
survival in macrophages ⓘ |
| optimalTemperature | cooler body sites ⓘ |
| order | Corynebacteriales NERFINISHED ⓘ |
| oxygenRequirement | aerobic ⓘ |
| phylum | Actinobacteria NERFINISHED ⓘ |
| preferredTissue |
peripheral nerves
ⓘ
skin ⓘ |
| primaryHost | human ⓘ |
| publicHealthRelevance | neglected tropical disease agent ⓘ |
| shape | rod-shaped ⓘ |
| stain |
Fite-Faraco positive
ⓘ
Ziehl–Neelsen positive ⓘ |
| taxonRank | species ⓘ |
| transmissionRoute |
prolonged close contact
ⓘ
respiratory droplets ⓘ |
| tropism |
Schwann cells
NERFINISHED
ⓘ
peripheral nerves ⓘ skin macrophages ⓘ |
| yearDiscovered | 1873 ⓘ |
| zoonoticReservoir |
nine-banded armadillo
ⓘ
red squirrel ⓘ |
Referenced by (4)
Full triples — surface form annotated when it differs from this entity's canonical label.