Marburg virus

E875939

Marburg virus is a highly lethal filovirus that causes severe hemorrhagic fever in humans and nonhuman primates, similar to Ebola.

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Observed surface forms (1)

Surface form Occurrences
Marburg marburgvirus 1

Statements (57)

Predicate Object
instanceOf filovirus
virus
BaltimoreClassification Group V (-ssRNA viruses)
biosafetyLevel BSL-4
caseFatalityRateRange 23–90 percent
causesDisease Marburg virus disease NERFINISHED
controlMeasures infection prevention and control in healthcare settings
supportive care
discoveredIn 1967
diseaseType viral hemorrhagic fever
entryReceptor NPC1 protein
enveloped true
family Filoviridae NERFINISHED
firstOutbreakAssociatedWith imported African green monkeys GENERATED
firstOutbreakLocation Belgrade, Yugoslavia NERFINISHED
Frankfurt, Germany NERFINISHED
Marburg, Germany NERFINISHED
genomeOrganization encodes seven structural proteins
genomePolarity negative-sense
genomeSegmentation nonsegmented
genomeType single-stranded RNA
genus Marburgvirus NERFINISHED
hasNoLicensedVaccine true GENERATED
hasNoSpecificAntiviralTreatment true GENERATED
host humans
nonhuman primates
inactivatedBy common disinfectants
heat
incubationPeriodRange 2–21 days
naturalReservoir Egyptian rousette bat NERFINISHED
Rousettus aegyptiacus NERFINISHED
notableOutbreakLocation Angola NERFINISHED
Democratic Republic of the Congo NERFINISHED
Equatorial Guinea NERFINISHED
Kenya NERFINISHED
Tanzania NERFINISHED
Uganda NERFINISHED
order Mononegavirales NERFINISHED
parentTaxon Marburg marburgvirus NERFINISHED
realm Riboviria NERFINISHED
relatedTo Ebola virus NERFINISHED
shape filamentous
pleomorphic
symptom abdominal pain
diarrhea
fever
hemorrhage
myalgia
severe headache
shock
vomiting
taxonRank species
transmissionRoute contact with infected blood
contact with infected body fluids
contact with infected tissues
exposure in mines or caves inhabited by bats
nosocomial transmission

Referenced by (2)

Full triples — surface form annotated when it differs from this entity's canonical label.

The Hot Zone subject Marburg virus
Filoviridae typeSpecies Marburg virus
this entity surface form: Marburg marburgvirus