Zabdeno
E854993
Zabdeno is a viral vector vaccine that uses a human adenovirus serotype 26 platform to provide protection against Ebola virus disease.
Statements (43)
| Predicate | Object |
|---|---|
| instanceOf |
Ebola vaccine
ⓘ
vaccine ⓘ viral vector vaccine ⓘ |
| belongsToClass | adenoviral vector vaccines ⓘ |
| containsVector | recombinant, replication-incompetent human adenovirus serotype 26 ⓘ |
| developedBy |
Janssen Vaccines & Prevention B.V.
NERFINISHED
ⓘ
Johnson & Johnson NERFINISHED ⓘ |
| elicitsImmuneResponse |
cell-mediated immune response against Ebola virus
ⓘ
humoral immune response against Ebola virus ⓘ |
| encodesAntigen | Ebola virus glycoprotein (GP) ⓘ |
| hasActiveSubstance | adenovirus type 26 vector encoding Ebola virus glycoprotein ⓘ |
| hasAdministrationRoute | parenteral ⓘ |
| hasAdministrationSchedule | prime dose followed by booster with Mvabea after an interval ⓘ |
| hasATCCode | J07BX06 ⓘ |
| hasBrandOwner | Janssen NERFINISHED ⓘ |
| hasCommonAdverseReaction |
fatigue
GENERATED
ⓘ
fever GENERATED ⓘ headache GENERATED ⓘ injection site pain GENERATED ⓘ myalgia GENERATED ⓘ |
| hasDosageForm | solution for injection ⓘ |
| hasINN | Ad26.ZEBOV ⓘ |
| hasLegalStatusInEU | prescription-only medicine ⓘ |
| hasMarketingAuthorisationHolder | Janssen-Cilag International NV NERFINISHED ⓘ |
| hasPharmaceuticalCompany | Janssen NERFINISHED ⓘ |
| hasRegulatoryAgency | European Medicines Agency NERFINISHED ⓘ |
| hasRouteOfAdministration | intramuscular injection ⓘ |
| hasStorageCondition | refrigerated storage ⓘ |
| hasTargetPathogenFamily | Filoviridae NERFINISHED ⓘ |
| hasTherapeuticArea |
infectious diseases
ⓘ
viral haemorrhagic fevers ⓘ |
| indicatedFor | active immunisation against Ebola virus disease caused by Zaire ebolavirus ⓘ |
| indicatedInAgeGroup | individuals 1 year of age and older ⓘ |
| isNonReplicating | true ⓘ |
| isPartOfRegimenWith | Mvabea NERFINISHED ⓘ |
| isUsedIn |
Ebola outbreak preparedness
ⓘ
Ebola vaccination campaigns in at-risk populations ⓘ |
| primeComponentOf | Zabdeno–Mvabea Ebola vaccine regimen NERFINISHED ⓘ |
| regimenType | prime-boost Ebola vaccination regimen ⓘ |
| targetsDisease | Ebola virus disease NERFINISHED ⓘ |
| targetsSpecies | Zaire ebolavirus NERFINISHED ⓘ |
| targetsVirus | Ebola virus NERFINISHED ⓘ |
| usesPlatform | human adenovirus serotype 26 ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject surface form:
human adenovirus serotype 26