Human mastadenovirus D
E854990
Human mastadenovirus D is a species of human adenoviruses that includes multiple serotypes, some of which are used as viral vectors in vaccine development and gene therapy.
Statements (46)
| Predicate | Object |
|---|---|
| instanceOf |
human adenovirus
ⓘ
virus species ⓘ |
| associatedWithDisease |
conjunctivitis
ⓘ
epidemic keratoconjunctivitis ⓘ gastroenteritis ⓘ pharyngoconjunctival fever ⓘ respiratory tract infections ⓘ |
| BaltimoreClassification | Group I dsDNA virus ⓘ |
| biosafetyLevel | typically handled at BSL-2 in laboratories ⓘ |
| capsidComposition | protein capsid ⓘ |
| capsidSymmetry | icosahedral ⓘ |
| clinicalRelevance |
important cause of ocular adenovirus infections
ⓘ
important in adenoviral vector design ⓘ |
| contains | multiple serotypes ⓘ |
| enveloped | non-enveloped ⓘ |
| environmentalStability | stable in the environment ⓘ |
| family | Adenoviridae NERFINISHED ⓘ |
| genomeSegmented | non-segmented ⓘ |
| genomeStructure | linear double-stranded DNA ⓘ |
| genomeType | double-stranded DNA virus ⓘ |
| genus | Mastadenovirus NERFINISHED ⓘ |
| hasGenome | linear dsDNA of approximately 34–36 kilobase pairs ⓘ |
| host | Homo sapiens NERFINISHED ⓘ |
| infects |
human conjunctival epithelial cells
ⓘ
human gastrointestinal epithelium ⓘ human respiratory tract epithelium ⓘ |
| naturalHost | human ⓘ |
| nucleicAcidType | DNA ⓘ |
| parentTaxon |
Adenoviridae
NERFINISHED
ⓘ
Human adenovirus D NERFINISHED ⓘ Mastadenovirus NERFINISHED ⓘ |
| particleType | non-segmented virion ⓘ |
| pathogenicFor |
immunocompetent humans
ⓘ
immunocompromised humans ⓘ |
| receptorUsage |
CD46 (for some serotypes)
NERFINISHED
ⓘ
sialic acid-containing glycans (for several serotypes) ⓘ |
| replicationCycle | lytic in permissive human cells ⓘ |
| replicationSite | nucleus of host cell ⓘ |
| resistance | resistant to many common disinfectants ⓘ |
| taxonRank | species ⓘ |
| transmissionRoute |
direct contact with contaminated surfaces
ⓘ
fecal-oral route ⓘ respiratory droplets ⓘ |
| usedAs | viral vector ⓘ |
| usedIn |
gene therapy research
ⓘ
vaccine development ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject surface form:
human adenovirus serotype 26