Lewontin’s paradox of variation
E760892
Lewontin’s paradox of variation is an evolutionary genetics puzzle highlighting that genetic diversity within species varies far less than expected from differences in their population sizes.
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
evolutionary genetics concept
ⓘ
population genetics puzzle ⓘ |
| addresses |
limits on neutral genetic variation in large populations
ⓘ
mismatch between theory and empirical genetic diversity ⓘ why species with huge population sizes do not have proportionally higher diversity ⓘ |
| appliesTo |
animals
ⓘ
microorganisms ⓘ plants ⓘ |
| basedOn | neutral theory of molecular evolution NERFINISHED ⓘ |
| category |
evolutionary paradox
ⓘ
genetic diversity paradox ⓘ |
| concerns |
effective population size
ⓘ
neutral genetic variation ⓘ within-species genetic diversity ⓘ |
| context | comparative studies of genetic diversity across taxa ⓘ |
| describes | discrepancy between genetic diversity and population size ⓘ |
| field |
evolutionary biology
ⓘ
population genetics ⓘ |
| highlights |
genetic diversity varies less than expected across species
ⓘ
weak correlation between census population size and genetic diversity ⓘ |
| involves |
background selection
ⓘ
demographic history ⓘ genetic drift ⓘ heterozygosity ⓘ life-history traits ⓘ linked selection ⓘ mutation rate ⓘ nucleotide diversity ⓘ population bottlenecks ⓘ population expansions ⓘ population structure ⓘ recombination rate variation ⓘ recurrent selective sweeps ⓘ |
| motivates |
comparative population genomics across species
ⓘ
study of effective population size reduction ⓘ study of selection at linked sites ⓘ |
| namedAfter | Richard C. Lewontin NERFINISHED ⓘ |
| observedUsing |
DNA sequence polymorphism data
ⓘ
allozyme data ⓘ genome-wide polymorphism data ⓘ |
| relatedTo |
nearly neutral theory of molecular evolution
NERFINISHED
ⓘ
neutral theory of genetic diversity ⓘ paradox of variation in molecular evolution ⓘ |
| suggests |
census population size is a poor predictor of genetic diversity
ⓘ
effective population sizes are constrained across species ⓘ strong selection can reduce neutral diversity ⓘ |
| usedIn |
interpretation of genome-wide diversity patterns
ⓘ
testing models of selection and demography ⓘ |
Referenced by (1)
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