Ras Initiative
E759510
Ras Initiative is a specialized research program focused on advancing the understanding and therapeutic targeting of RAS-driven cancers.
Statements (34)
| Predicate | Object |
|---|---|
| instanceOf |
cancer research program
ⓘ
research initiative ⓘ |
| aimsTo |
develop RAS-targeted therapies
ⓘ
identify vulnerabilities in RAS-driven tumors ⓘ improve understanding of RAS biology ⓘ translate basic RAS research into clinical applications ⓘ |
| collaboratesWith |
academic researchers
ⓘ
biotechnology companies ⓘ pharmaceutical companies ⓘ |
| focusesOn |
RAS-driven cancers
ⓘ
oncogenic RAS signaling ⓘ therapeutic targeting of RAS ⓘ |
| goal |
enable development of effective RAS inhibitors
ⓘ
improve outcomes for patients with RAS-driven cancers ⓘ |
| hasResearchArea |
cancer biology
ⓘ
drug discovery ⓘ molecular oncology ⓘ signal transduction ⓘ targeted cancer therapy ⓘ |
| studiesDisease |
colorectal cancer
ⓘ
lung cancer ⓘ pancreatic cancer ⓘ |
| studiesGene |
HRAS
ⓘ
KRAS NERFINISHED ⓘ NRAS NERFINISHED ⓘ |
| studiesProcess |
RAS signal transduction pathways
ⓘ
drug resistance in RAS-driven cancers ⓘ oncogenic transformation ⓘ tumor progression ⓘ |
| usesMethod |
animal models of cancer
ⓘ
biochemical assays ⓘ cell-based models ⓘ high-throughput screening ⓘ structural biology ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.