Leishmania donovani
E731212
Leishmania donovani is a protozoan parasite that causes visceral leishmaniasis (kala-azar) in humans, primarily affecting internal organs such as the liver, spleen, and bone marrow.
Statements (50)
| Predicate | Object |
|---|---|
| instanceOf |
kinetoplastid
ⓘ
protozoan parasite ⓘ unicellular eukaryote ⓘ |
| affectsOrgan |
bone marrow
ⓘ
liver ⓘ lymph nodes ⓘ spleen ⓘ |
| associatedSymptom |
anemia
GENERATED
ⓘ
hepatosplenomegaly GENERATED ⓘ pancytopenia GENERATED ⓘ prolonged fever GENERATED ⓘ weight loss GENERATED ⓘ |
| causes |
kala-azar
ⓘ
visceral leishmaniasis ⓘ |
| class | Kinetoplastea NERFINISHED ⓘ |
| diagnosticMethod |
PCR
ⓘ
bone marrow aspirate microscopy ⓘ serology ⓘ splenic aspirate microscopy ⓘ |
| diseaseType | systemic infection ⓘ |
| domain |
Eukarya
ⓘ
surface form:
Eukaryota
|
| drugResistanceConcern | antimonial drugs ⓘ |
| drugSusceptibility |
amphotericin B
NERFINISHED
ⓘ
liposomal amphotericin B ⓘ miltefosine NERFINISHED ⓘ paromomycin NERFINISHED ⓘ |
| family | Trypanosomatidae NERFINISHED ⓘ |
| firstDescribedAsPathogenOf | visceral leishmaniasis in India ⓘ |
| genus | Leishmania NERFINISHED ⓘ |
| geographicDistribution |
East Africa
NERFINISHED
ⓘ
Indian subcontinent NERFINISHED ⓘ Mediterranean region ⓘ |
| hasOrganelle | kinetoplast ⓘ |
| host |
dog
ⓘ
human ⓘ other mammals ⓘ |
| lifeCycleStage |
amastigote
ⓘ
promastigote ⓘ |
| locationInHost |
macrophages
ⓘ
reticuloendothelial system ⓘ |
| locationInVector | midgut of sandfly ⓘ |
| order | Trypanosomatida NERFINISHED ⓘ |
| phylum | Euglenozoa NERFINISHED ⓘ |
| reproduction |
asexual reproduction in vertebrate host
ⓘ
sexual or genetic exchange in sandfly vector ⓘ |
| taxonRank | species ⓘ |
| transmissionCycle |
anthroponotic in Indian subcontinent
ⓘ
zoonotic in some regions ⓘ |
| transmissionRoute | sandfly bite ⓘ |
| vector | Phlebotomus sandflies NERFINISHED ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.