Office for Human Research Protections
E722077
The Office for Human Research Protections is a U.S. federal agency that safeguards the rights and welfare of people participating in research conducted or supported by the Department of Health and Human Services.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Office for Human Research Protections canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T8264139 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Office for Human Research Protections Context triple: [OASH, oversightOf, Office for Human Research Protections]
-
A.
Institutional Review Board
An Institutional Review Board is a committee that reviews and monitors research involving human participants to ensure ethical standards and participant protections are upheld.
-
B.
Office of Research Integrity
The Office of Research Integrity is a U.S. federal agency responsible for promoting research integrity and investigating allegations of research misconduct in Public Health Service–funded research.
-
C.
Center for Scientific Review
The Center for Scientific Review is the National Institutes of Health component responsible for overseeing the peer review of most grant applications to ensure scientific merit and integrity in funding decisions.
-
D.
IRB
IRB is the acronym commonly used for the Irish Republican Brotherhood, a secret oath-bound organization that sought to establish an independent Irish republic in the late 19th and early 20th centuries.
-
E.
National Institutes of Health
The National Institutes of Health is the United States’ primary federal biomedical research agency, supporting and conducting medical research to improve public health.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Office for Human Research Protections Target entity description: The Office for Human Research Protections is a U.S. federal agency that safeguards the rights and welfare of people participating in research conducted or supported by the Department of Health and Human Services.
-
A.
Institutional Review Board
An Institutional Review Board is a committee that reviews and monitors research involving human participants to ensure ethical standards and participant protections are upheld.
-
B.
Office of Research Integrity
The Office of Research Integrity is a U.S. federal agency responsible for promoting research integrity and investigating allegations of research misconduct in Public Health Service–funded research.
-
C.
Center for Scientific Review
The Center for Scientific Review is the National Institutes of Health component responsible for overseeing the peer review of most grant applications to ensure scientific merit and integrity in funding decisions.
-
D.
IRB
IRB is the acronym commonly used for the Irish Republican Brotherhood, a secret oath-bound organization that sought to establish an independent Irish republic in the late 19th and early 20th centuries.
-
E.
National Institutes of Health
The National Institutes of Health is the United States’ primary federal biomedical research agency, supporting and conducting medical research to improve public health.
- F. None of above. chosen
Statements (47)
| Predicate | Object |
|---|---|
| instanceOf |
federal agency
ⓘ
regulatory agency ⓘ |
| abbreviation | OHRP NERFINISHED ⓘ |
| areaOfRegulation |
biomedical human subjects research
ⓘ
social and behavioral human subjects research ⓘ |
| audience |
institutional review boards
ⓘ
investigators conducting human subjects research ⓘ research institutions ⓘ research participants and the public ⓘ |
| canImpose |
restrictions on institutions’ HHS research funding for noncompliance
ⓘ
suspension of research activities for serious noncompliance ⓘ |
| collaboratesWith |
Food and Drug Administration
NERFINISHED
ⓘ
other federal departments and agencies that follow the Common Rule ⓘ |
| country |
United States of America
ⓘ
surface form:
United States
|
| focus |
IRB review and approval of research
ⓘ
ethical conduct of human subjects research ⓘ informed consent requirements in research ⓘ protection of human subjects in research ⓘ |
| goal | to ensure that human subjects are protected in research consistent with ethical principles and regulatory requirements ⓘ |
| issues |
determination letters regarding compliance with human subjects regulations
ⓘ
guidance documents on human research protections ⓘ |
| jurisdiction |
federally conducted research
ⓘ
federally supported research ⓘ |
| language | English ⓘ |
| legalBasis |
HHS regulations at 45 CFR part 46
ⓘ
U.S. Common Rule as implemented by HHS NERFINISHED ⓘ |
| locatedIn | Washington, D.C. ⓘ |
| mission | to protect the rights, welfare, and wellbeing of human subjects involved in research conducted or supported by HHS ⓘ |
| oversees | Federalwide Assurances (FWAs) for the protection of human subjects NERFINISHED ⓘ |
| parentAgency | U.S. Department of Health and Human Services NERFINISHED ⓘ |
| partOf | U.S. Public Health Service (regulatory structure) NERFINISHED ⓘ |
| regulates |
institutional review boards (IRBs) engaged in HHS-supported research
ⓘ
institutions conducting HHS-supported human subjects research ⓘ |
| relatedConcept |
Belmont Report
NERFINISHED
ⓘ
Common Rule NERFINISHED ⓘ |
| responsibility |
assurance of compliance for institutions conducting HHS-supported human subjects research
ⓘ
compliance oversight of institutions engaged in HHS-conducted or -supported human subjects research ⓘ education and outreach on human research protections ⓘ interpretation and enforcement of the Common Rule for HHS ⓘ oversight of HHS regulations for the protection of human subjects ⓘ policy guidance on human research protections ⓘ registration of institutional review boards ⓘ |
| sector |
behavioral research
ⓘ
biomedical research ⓘ health research ⓘ |
| subordinateTo | Office of the Assistant Secretary for Health NERFINISHED ⓘ |
| website | https://www.hhs.gov/ohrp/ ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Office for Human Research Protections Description of subject: The Office for Human Research Protections is a U.S. federal agency that safeguards the rights and welfare of people participating in research conducted or supported by the Department of Health and Human Services.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.