Leloir pathway of galactose metabolism

E715835

The Leloir pathway of galactose metabolism is the primary biochemical route by which cells convert galactose into glucose-1-phosphate for entry into central energy and biosynthetic pathways.

All labels observed (1)

Label Occurrences
Leloir pathway of galactose metabolism canonical 1

How this entity was disambiguated

Statements (49)

Predicate Object
instanceOf galactose catabolic pathway ⓘ
metabolic pathway ⓘ
associatedWithDisease classic galactosemia ⓘ
epimerase deficiency galactosemia ⓘ
galactokinase deficiency ⓘ
convertsTo galactose-1-phosphate ⓘ
glucose-1-phosphate ⓘ
discoveredBy Luis Federico Leloir NERFINISHED ⓘ
discoveryAward Nobel Prize in Chemistry 1970 NERFINISHED ⓘ
essentialFor lactose metabolism ⓘ
utilization of dietary galactose ⓘ
feedsInto glycogen synthesis via glucose-1-phosphate ⓘ
glycolysis via glucose-6-phosphate ⓘ
foundInTaxon Escherichia coli NERFINISHED ⓘ
Homo sapiens NERFINISHED ⓘ
Mus musculus NERFINISHED ⓘ
Saccharomyces cerevisiae NERFINISHED ⓘ
hasCofactor ATP ⓘ
NAD+ ⓘ
UTP ⓘ
hasEnzyme UDP-galactose 4-epimerase NERFINISHED ⓘ
galactokinase ⓘ
galactose-1-phosphate uridylyltransferase ⓘ
hasInput D-galactose ⓘ
hasOutput UDP-galactose ⓘ
UDP-glucose ⓘ
glucose-1-phosphate ⓘ
hasPrimaryFunction conversion of galactose to glucose-1-phosphate ⓘ
hasStep UDP-galactose 4-epimerase reaction ⓘ
galactokinase reaction ⓘ
galactose-1-phosphate uridylyltransferase reaction ⓘ
linkedToPathway gluconeogenesis ⓘ
glycogen metabolism ⓘ
glycolysis ⓘ
namedAfter Luis Federico Leloir NERFINISHED ⓘ
occursIn cytosol ⓘ
partOf carbohydrate metabolism ⓘ
central carbon metabolism ⓘ
energy metabolism ⓘ
galactose metabolism ⓘ
providesPrecursorFor glycolipid biosynthesis ⓘ
glycoprotein biosynthesis ⓘ
regulatesLevelOf UDP-galactose ⓘ
galactose ⓘ
subclassOf carbohydrate metabolism pathway ⓘ
monosaccharide metabolism pathway ⓘ
usesIntermediate UDP-galactose ⓘ
UDP-glucose ⓘ
galactose-1-phosphate ⓘ

How these facts were elicited

Referenced by (1)

Full triples — surface form annotated when it differs from this entity's canonical label.

Luis Federico Leloir → knownFor → Leloir pathway of galactose metabolism ⓘ