Akira Endo
E69517
Akira Endo is a Japanese biochemist best known for discovering statins, the cholesterol-lowering drugs that revolutionized cardiovascular medicine.
Statements (44)
| Predicate | Object |
|---|---|
| instanceOf |
biochemist
→
human → scientist → |
| academicDegree |
Doctor of Agriculture
→
|
| awardReceived |
Canada Gairdner International Award
→
Japan Prize → Lasker-DeBakey Clinical Medical Research Award → Massry Prize → Order of Culture (Japan) → Warren Alpert Foundation Prize → |
| contributedTo |
reduction of cardiovascular disease mortality
→
|
| countryOfCitizenship |
Japan
→
|
| educatedAt |
Tohoku University
NERFINISHED
→
|
| employer |
Sankyo Company
→
Tokyo University of Agriculture and Technology NERFINISHED → |
| ethnicGroup |
Japanese
→
|
| fieldOfWork |
biochemistry
→
cardiovascular medicine → pharmacology → |
| hasImpactOn |
cardiovascular medicine
→
public health → |
| hasResearchArea |
atherosclerosis prevention
→
lipid metabolism → |
| honorificTitle |
pioneer of statins
→
|
| influenced |
development of other statin drugs
→
development of pravastatin → development of simvastatin → |
| knownFor |
development of HMG-CoA reductase inhibitors
→
discovery of compactin (ML-236B) → pioneering work on statin drugs → |
| languageOfWorkOrName |
Japanese
→
|
| memberOf |
Japan Academy
→
|
| notableAchievement |
first demonstration that HMG-CoA reductase inhibition lowers cholesterol in animals
→
|
| notableFor |
cholesterol-lowering drugs
→
discovery of statins → inhibition of HMG-CoA reductase → |
| notableWork |
identification of fungal metabolites that inhibit HMG-CoA reductase
→
|
| occupation |
biochemist
→
researcher → |
| placeOfBirth |
Akita Prefecture
NERFINISHED
→
|
| researchFocus |
cholesterol biosynthesis
→
enzyme inhibitors → fungal metabolites → |
| sexOrGender |
male
→
|
Referenced by (1)
| Subject (surface form when different) | Predicate |
|---|---|
|
Tohoku University
→
|
hasNotableAlumni |