Akira Endo

E69517

Akira Endo is a Japanese biochemist best known for discovering statins, the cholesterol-lowering drugs that revolutionized cardiovascular medicine.

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Akira Endo canonical 2

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Statements (44)

Predicate Object
instanceOf biochemist
human
scientist
academicDegree Doctor of Agriculture
awardReceived Gairdner Foundation International Award
surface form: Canada Gairdner International Award

Japan Prize
Lasker~DeBakey Clinical Medical Research Award
surface form: Lasker-DeBakey Clinical Medical Research Award

Massry Prize
Order of Culture
surface form: Order of Culture (Japan)

Warren Alpert Foundation Prize
contributedTo reduction of cardiovascular disease mortality
countryOfCitizenship Japan
educatedAt Tohoku University
employer Sankyo Company
Tokyo University of Agriculture (Meguro campus)
surface form: Tokyo University of Agriculture and Technology
ethnicGroup Japanese
fieldOfWork biochemistry
cardiovascular medicine
pharmacology
hasImpactOn cardiovascular medicine
public health
hasResearchArea atherosclerosis prevention
lipid metabolism
honorificTitle pioneer of statins
influenced development of other statin drugs
development of pravastatin
development of simvastatin
knownFor development of HMG-CoA reductase inhibitors
discovery of compactin (ML-236B)
pioneering work on statin drugs
languageOfWorkOrName Japanese
memberOf Japan Academy
notableAchievement first demonstration that HMG-CoA reductase inhibition lowers cholesterol in animals
notableFor cholesterol-lowering drugs
discovery of statins
inhibition of HMG-CoA reductase
notableWork identification of fungal metabolites that inhibit HMG-CoA reductase
occupation biochemist
researcher
placeOfBirth Akita Prefecture
researchFocus cholesterol biosynthesis
enzyme inhibitors
fungal metabolites
sexOrGender male

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Referenced by (2)

Full triples — surface form annotated when it differs from this entity's canonical label.

TU hasNotableAlumni Akira Endo
subject surface form: Tohoku University