Ion Torrent
E659392
DNA sequencing technology platform
next-generation sequencing technology
semiconductor-based sequencing platform
Ion Torrent is a DNA sequencing technology platform known for its semiconductor-based sequencing method that detects hydrogen ions released during nucleotide incorporation.
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
DNA sequencing technology platform
ⓘ
next-generation sequencing technology ⓘ semiconductor-based sequencing platform ⓘ |
| acquiredBy |
Life Technologies Corporation
NERFINISHED
ⓘ
Thermo Fisher Scientific NERFINISHED ⓘ |
| acquisitionYear | 2010 ⓘ |
| advantage |
lower instrument cost compared to optical systems
ⓘ
no need for lasers or cameras ⓘ potentially faster run times ⓘ |
| dataFormat | standard sequence reads ⓘ |
| detects |
hydrogen ions
ⓘ
pH changes ⓘ |
| developedBy | Ion Torrent Systems, Inc. NERFINISHED ⓘ |
| doesNotRequire |
fluorescently labeled nucleotides
ⓘ
optical detection ⓘ |
| foundedBy | Jonathan M. Rothberg NERFINISHED ⓘ |
| hasChipType |
Ion 314 chip
NERFINISHED
ⓘ
Ion 316 chip NERFINISHED ⓘ Ion 318 chip NERFINISHED ⓘ Ion PI chip NERFINISHED ⓘ Ion PII chip NERFINISHED ⓘ Ion PIII chip NERFINISHED ⓘ |
| hasPlatform |
Ion GeneStudio S5
NERFINISHED
ⓘ
Ion PGM NERFINISHED ⓘ Ion Proton NERFINISHED ⓘ Ion S5 NERFINISHED ⓘ Ion S5 XL NERFINISHED ⓘ |
| libraryPreparation | emulsion PCR on beads ⓘ |
| limitation | homopolymer length estimation errors ⓘ |
| measures | changes in pH caused by nucleotide incorporation ⓘ |
| outputType | short-read sequences ⓘ |
| readout | electrical signal ⓘ |
| sequencingChemistry | sequencing by synthesis ⓘ |
| sequencingPrinciple | detection of hydrogen ions released during nucleotide incorporation ⓘ |
| supports |
barcoded libraries
ⓘ
multiplexed sequencing ⓘ |
| templateAttachment | DNA bound to beads loaded into wells ⓘ |
| usedFor |
DNA sequencing
ⓘ
amplicon sequencing ⓘ clinical diagnostics ⓘ exome sequencing ⓘ metagenomics ⓘ microbial genome sequencing ⓘ oncology panel testing ⓘ targeted sequencing ⓘ |
| uses |
ion-sensitive field-effect transistor sensors
ⓘ
microfabricated semiconductor chip ⓘ |
| usesMethod | semiconductor sequencing ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.