bacteriophage lambda
E629012
Bacteriophage lambda is a temperate virus that infects Escherichia coli and serves as a classic model system for studying gene regulation, lysogeny, and molecular genetics.
Statements (61)
| Predicate | Object |
|---|---|
| instanceOf |
Siphoviridae
ⓘ
double-stranded DNA virus ⓘ temperate bacteriophage ⓘ virus ⓘ |
| belongsToFamily | Siphoviridae NERFINISHED ⓘ |
| belongsToOrder | Caudovirales NERFINISHED ⓘ |
| cosSiteLength | 12 nucleotides ⓘ |
| decisionProcess | lysis-lysogeny switch ⓘ |
| discoveredBy | Esther Lederberg NERFINISHED ⓘ |
| discoveryYear | 1950 ⓘ |
| encodes |
CI repressor
ⓘ
CII protein NERFINISHED ⓘ CIII protein ⓘ Cro protein NERFINISHED ⓘ Gam protein NERFINISHED ⓘ Int integrase ⓘ N antiterminator protein ⓘ Q antiterminator protein ⓘ Red recombination proteins ⓘ Xis excisionase ⓘ head and tail structural proteins ⓘ |
| genomeSize | approximately 48.5 kilobase pairs ⓘ |
| genomeType | linear double-stranded DNA ⓘ |
| hasCohesiveEnds | cos sites ⓘ |
| hasGCContent | approximately 50 percent ⓘ |
| hasLifeCycle |
lysogenic cycle
ⓘ
lytic cycle ⓘ |
| hasMorphology | icosahedral head with long noncontractile tail ⓘ |
| hasOperator |
OL operator region
ⓘ
OR operator region ⓘ |
| hasPackagingLimit | approximately 52 kilobase pairs ⓘ |
| hasRegulatoryRegion |
PL promoter
ⓘ
PR promoter ⓘ PRM promoter ⓘ |
| host | Escherichia coli K-12 NERFINISHED ⓘ |
| inducedBy | DNA damage ⓘ |
| inductionMechanism | SOS response mediated CI cleavage ⓘ |
| infects | Escherichia coli NERFINISHED ⓘ |
| integratesInto | E. coli chromosome ⓘ |
| integrationSite |
attB site in E. coli
ⓘ
between gal and bio operons in E. coli ⓘ |
| isTemperate | true ⓘ |
| keyRegulator |
CI repressor
ⓘ
Cro protein NERFINISHED ⓘ |
| keyRegulator |
CII protein
NERFINISHED
ⓘ
N protein ⓘ Q protein NERFINISHED ⓘ |
| prophageForm | integrated into host chromosome ⓘ |
| repressorMaintains | prophage state ⓘ |
| requiresForIntegration | host IHF protein ⓘ |
| requiresForReplication | host DNA replication machinery ⓘ |
| tailType | long noncontractile tail ⓘ |
| taxonRank | species ⓘ |
| usedAs |
cloning vector
ⓘ
phage display vector ⓘ |
| usedAsModelFor |
developmental decision-making in phages
ⓘ
gene regulation ⓘ lysogeny ⓘ molecular genetics ⓘ site-specific recombination ⓘ transcriptional regulation ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.