Joseph L. Goldstein
E620202
Joseph L. Goldstein is an American biochemist and geneticist, Nobel Prize laureate, renowned for his pioneering work on cholesterol metabolism and the regulation of low-density lipoprotein (LDL) receptors.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Joseph L. Goldstein canonical | 1 |
Statements (45)
| Predicate | Object |
|---|---|
| instanceOf |
American scientist
ⓘ
Nobel laureate ⓘ biochemist ⓘ geneticist ⓘ human ⓘ |
| awardReceived |
Gairdner Foundation International Award
NERFINISHED
ⓘ
Lasker Award NERFINISHED ⓘ Louisa Gross Horwitz Prize NERFINISHED ⓘ National Medal of Science ⓘ Nobel Prize in Physiology or Medicine ⓘ |
| coAuthorWith | Michael S. Brown NERFINISHED ⓘ |
| countryOfCitizenship | United States of America ⓘ |
| doctoralStudent | Michael S. Brown NERFINISHED ⓘ |
| educatedAt |
University of Texas Southwestern Medical School
NERFINISHED
ⓘ
Washington and Lee University NERFINISHED ⓘ |
| employer | University of Texas Southwestern Medical Center NERFINISHED ⓘ |
| familyName | Goldstein NERFINISHED ⓘ |
| fieldOfWork |
biochemistry
ⓘ
cell biology ⓘ cholesterol metabolism ⓘ genetics ⓘ lipid metabolism ⓘ |
| gender | male ⓘ |
| givenName | Joseph NERFINISHED ⓘ |
| hasAcademicAdvisor | Donald Seldin NERFINISHED ⓘ |
| influenced | development of cholesterol-lowering drugs ⓘ |
| knownFor |
demonstrating the role of LDL receptors in familial hypercholesterolemia
ⓘ
linking LDL receptor defects to atherosclerosis risk ⓘ pioneering work that enabled development of statin therapies ⓘ |
| languageSpoken | English ⓘ |
| memberOf |
American Academy of Arts and Sciences
ⓘ
Institute of Medicine of the National Academies NERFINISHED ⓘ National Academy of Sciences ⓘ |
| name | Joseph L. Goldstein NERFINISHED ⓘ |
| notableAchievement |
clarified feedback regulation of cholesterol synthesis
ⓘ
helped establish receptor-mediated endocytosis as a key biological process ⓘ |
| notableFor |
elucidation of cholesterol metabolism regulation
ⓘ
research on low-density lipoprotein receptors ⓘ |
| occupation |
medical researcher
ⓘ
university professor ⓘ |
| researchFocus |
familial hypercholesterolemia
ⓘ
lipoprotein receptors ⓘ regulation of cholesterol biosynthesis ⓘ |
| sharedNobelPrizeWith | Michael S. Brown NERFINISHED ⓘ |
| workLocation | Dallas, Texas NERFINISHED ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.