Tiglutik
E561111
Tiglutik is an oral suspension formulation of the ALS medication riluzole, designed to help slow disease progression in patients with amyotrophic lateral sclerosis.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Tiglutik canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T6005042 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Tiglutik Context triple: [Riluzole, hasBrandName, Tiglutik]
-
A.
Tigak
Tigak is an Austronesian language of the Meso-Melanesian subgroup spoken primarily in parts of Papua New Guinea.
-
B.
Tappara
Tappara is a prominent professional ice hockey club from Tampere, Finland, known as one of the most successful and historic teams in the Finnish Liiga.
-
C.
The Turim
The Turim is a foundational 14th-century Jewish legal code by Rabbi Jacob ben Asher that systematically organizes halakhic rulings into four major sections.
-
D.
Tikkana
Tikkana was a prominent 13th-century Telugu poet and scholar best known for translating a major portion of the Mahabharata into Telugu and helping shape classical Telugu literature.
-
E.
Tidan
Tidan is a river in southwestern Sweden that flows through the historical province of Västergötland.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Tiglutik Target entity description: Tiglutik is an oral suspension formulation of the ALS medication riluzole, designed to help slow disease progression in patients with amyotrophic lateral sclerosis.
-
A.
Tigak
Tigak is an Austronesian language of the Meso-Melanesian subgroup spoken primarily in parts of Papua New Guinea.
-
B.
Tappara
Tappara is a prominent professional ice hockey club from Tampere, Finland, known as one of the most successful and historic teams in the Finnish Liiga.
-
C.
The Turim
The Turim is a foundational 14th-century Jewish legal code by Rabbi Jacob ben Asher that systematically organizes halakhic rulings into four major sections.
-
D.
Tikkana
Tikkana was a prominent 13th-century Telugu poet and scholar best known for translating a major portion of the Mahabharata into Telugu and helping shape classical Telugu literature.
-
E.
Tidan
Tidan is a river in southwestern Sweden that flows through the historical province of Västergötland.
- F. None of above. chosen
Statements (28)
| Predicate | Object |
|---|---|
| instanceOf |
oral suspension
ⓘ
pharmaceutical drug ⓘ |
| activeIngredient | riluzole ⓘ |
| containsDosageForm | oral liquid ⓘ |
| containsSubstance | riluzole ⓘ |
| dosageForm | oral suspension ⓘ |
| drugClass | glutamate release inhibitor ⓘ |
| formulationType | ready-to-use suspension ⓘ |
| hasAdministrationAdvantage | facilitates dosing in patients with swallowing difficulties ⓘ |
| hasTradeName | Tiglutik NERFINISHED ⓘ |
| indication |
ALS
NERFINISHED
ⓘ
amyotrophic lateral sclerosis ⓘ |
| indicationDetail | treatment of patients with amyotrophic lateral sclerosis to extend survival or time to tracheostomy ⓘ |
| intendedUse | management of ALS ⓘ |
| isFormulationOf | riluzole NERFINISHED ⓘ |
| mechanismOfAction |
inactivates voltage-dependent sodium channels
ⓘ
inhibits glutamate release ⓘ interferes with intracellular events following excitatory amino acid receptor activation ⓘ |
| pharmacologicalClass | neuroprotective agent ⓘ |
| regulatoryStatus | prescription only ⓘ |
| routeOfAdministration | oral ⓘ |
| targetPopulation | adult patients with ALS ⓘ |
| therapeuticArea |
neurodegenerative diseases
ⓘ
neurology ⓘ |
| therapeuticEffect | slows disease progression in ALS ⓘ |
| treatmentGoal |
prolong survival in ALS patients
ⓘ
slow progression of ALS ⓘ |
| treatsSymptom | functional decline in ALS ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Tiglutik Description of subject: Tiglutik is an oral suspension formulation of the ALS medication riluzole, designed to help slow disease progression in patients with amyotrophic lateral sclerosis.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject surface form:
Riluzole