Gemin6
E561088
Gemin6 is a component of the SMN (survival motor neuron) complex involved in the assembly and maturation of small nuclear ribonucleoproteins essential for pre-mRNA splicing.
Observed surface forms (1)
| Surface form | Occurrences |
|---|---|
| GEMIN6 gene | 0 |
Statements (43)
| Predicate | Object |
|---|---|
| instanceOf |
SMN complex component
ⓘ
protein ⓘ protein-coding gene ⓘ |
| associatedWith |
SMN complex
NERFINISHED
ⓘ
motor neuron function ⓘ spinal muscular atrophy pathway ⓘ |
| binds |
Gemin7
ⓘ
SMN1 protein NERFINISHED ⓘ |
| biologicalProcess |
RNA splicing
ⓘ
U snRNP assembly ⓘ mRNA processing ⓘ |
| cellularComponent |
SMN complex
NERFINISHED
ⓘ
cytoplasmic ribonucleoprotein granule ⓘ nuclear body ⓘ |
| conservedIn |
metazoans
ⓘ
vertebrates ⓘ |
| encodedBy | GEMIN6 gene NERFINISHED ⓘ |
| encodes | Gemin6 NERFINISHED ⓘ |
| expressedIn |
human cells
ⓘ
neuronal tissue ⓘ |
| formsComplexWith |
Gemin2
NERFINISHED
ⓘ
Gemin3 NERFINISHED ⓘ Gemin4 NERFINISHED ⓘ Gemin5 NERFINISHED ⓘ Gemin7 ⓘ SMN1 protein NERFINISHED ⓘ |
| involvedIn | spliceosome biogenesis ⓘ |
| locatedIn |
Cajal bodies
NERFINISHED
ⓘ
Gems ⓘ cytoplasm ⓘ nucleus ⓘ |
| locatedOn | human chromosome 2 ⓘ |
| molecularFunction |
RNA binding
ⓘ
protein binding ⓘ |
| orthologOf |
mouse Gemin6
ⓘ
zebrafish Gemin6 NERFINISHED ⓘ |
| participatesIn |
pre-mRNA splicing
ⓘ
small nuclear ribonucleoprotein assembly ⓘ snRNP maturation ⓘ |
| partOf | SMN complex NERFINISHED ⓘ |
| requiredFor |
efficient snRNP assembly
ⓘ
proper spliceosome function ⓘ |
| taxon | Homo sapiens NERFINISHED ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject surface form:
Survival motor neuron protein