Gemin5

E561087
RNA-binding protein component of SMN complex protein

Gemin5 is an RNA-binding protein that is part of the SMN complex and plays a key role in small nuclear ribonucleoprotein (snRNP) assembly and pre-mRNA splicing.

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Statements (39)

Predicate Object
instanceOf RNA-binding protein ⓘ
component of SMN complex ⓘ
protein ⓘ
alternativeName GEMIN5 NERFINISHED ⓘ
gem-associated protein 5 NERFINISHED ⓘ
associatedWithDisease spinal muscular atrophy pathway ⓘ
associatedWithProcess gene expression regulation at RNA level ⓘ
mRNA translation control ⓘ
neuronal RNA metabolism ⓘ
snRNP biogenesis ⓘ
spliceosome assembly ⓘ
bindsMolecule RNA ⓘ
cellularComponent SMN complex NERFINISHED ⓘ
cytoplasm ⓘ
nucleus ⓘ
containsDomain RNA-binding domain ⓘ
WD repeat domain ⓘ
encodedBy GEMIN5 gene NERFINISHED ⓘ
hasRole snRNA recognition ⓘ
snRNP core particle formation ⓘ
interactsWith Gemin2 NERFINISHED ⓘ
Gemin3 NERFINISHED ⓘ
Gemin4 NERFINISHED ⓘ
Gemin6 NERFINISHED ⓘ
Gemin7 ⓘ
SMN1 protein NERFINISHED ⓘ
Sm proteins ⓘ
isConservedIn mammals ⓘ
vertebrates ⓘ
molecularFunction RNA binding ⓘ
protein binding ⓘ
snRNA binding ⓘ
translation regulation ⓘ
organism Homo sapiens NERFINISHED ⓘ
participatesIn pre-mRNA splicing ⓘ
small nuclear ribonucleoprotein assembly ⓘ
regulates snRNP availability for splicing ⓘ
subcellularLocalization Cajal bodies NERFINISHED ⓘ
nuclear gems ⓘ

Referenced by (1)

Full triples — surface form annotated when it differs from this entity's canonical label.

survival motor neuron protein → formsComplexWith → Gemin5 ⓘ
subject surface form: Survival motor neuron protein