Cajal bodies
E561083
Cajal bodies are dynamic nuclear suborganelles involved in the biogenesis and maturation of small nuclear ribonucleoproteins (snRNPs) and other RNA-processing factors.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Cajal bodies canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T6004669 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Cajal bodies Context triple: [Survival motor neuron protein, cellularLocation, Cajal bodies]
-
A.
P-body
The P-body was General Motors' compact mid-engine car platform developed specifically for the Pontiac Fiero in the 1980s.
-
B.
Golgi apparatus
The Golgi apparatus is a membrane-bound organelle in eukaryotic cells that modifies, sorts, and packages proteins and lipids for secretion or delivery to other cellular destinations.
-
C.
Molecular Biology of the Cell
Molecular Biology of the Cell is a leading peer-reviewed scientific journal that publishes research and reviews in cell biology and related molecular life sciences.
-
D.
Molecular Biology of the Cell
Molecular Biology of the Cell is a widely used, authoritative textbook that provides a comprehensive introduction to the fundamental concepts and mechanisms of modern cell biology.
-
E.
Virchow–Robin spaces
Virchow–Robin spaces are perivascular, fluid-filled spaces that surround blood vessels as they penetrate the brain, visible on neuroimaging and often associated with various neurological conditions.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Cajal bodies Target entity description: Cajal bodies are dynamic nuclear suborganelles involved in the biogenesis and maturation of small nuclear ribonucleoproteins (snRNPs) and other RNA-processing factors.
-
A.
P-body
The P-body was General Motors' compact mid-engine car platform developed specifically for the Pontiac Fiero in the 1980s.
-
B.
Golgi apparatus
The Golgi apparatus is a membrane-bound organelle in eukaryotic cells that modifies, sorts, and packages proteins and lipids for secretion or delivery to other cellular destinations.
-
C.
Molecular Biology of the Cell
Molecular Biology of the Cell is a leading peer-reviewed scientific journal that publishes research and reviews in cell biology and related molecular life sciences.
-
D.
Molecular Biology of the Cell
Molecular Biology of the Cell is a widely used, authoritative textbook that provides a comprehensive introduction to the fundamental concepts and mechanisms of modern cell biology.
-
E.
Virchow–Robin spaces
Virchow–Robin spaces are perivascular, fluid-filled spaces that surround blood vessels as they penetrate the brain, visible on neuroimaging and often associated with various neurological conditions.
- F. None of above. chosen
Statements (49)
| Predicate | Object |
|---|---|
| instanceOf |
biomolecular condensate
ⓘ
membraneless organelle ⓘ nuclear suborganelle ⓘ |
| alsoKnownAs | coiled bodies NERFINISHED ⓘ |
| associatedWith |
RNA polymerase II transcription
ⓘ
small nuclear RNAs ⓘ small nucleolar RNAs ⓘ telomerase RNA component ⓘ |
| closelyAssociatedWith | nucleolus ⓘ |
| contains |
Nopp140
NERFINISHED
ⓘ
SMN complex NERFINISHED ⓘ coilin ⓘ fibrillarin NERFINISHED ⓘ scaRNAs ⓘ spliceosomal snRNPs ⓘ survival motor neuron protein NERFINISHED ⓘ |
| disassemblesDuring | mitosis ⓘ |
| dysfunctionAssociatedWith |
neurodegenerative diseases
ⓘ
spinal muscular atrophy ⓘ |
| formsBy | liquid–liquid phase separation ⓘ |
| foundIn |
Drosophila cells
ⓘ
plant cells ⓘ vertebrate cells ⓘ |
| hasCharacteristic |
dynamic
ⓘ
membrane-less ⓘ spherical ⓘ variable number per nucleus ⓘ |
| hasMarkerProtein | coilin ⓘ |
| identifiedBy | anti-coilin antibodies ⓘ |
| involvedIn |
RNA processing
ⓘ
small nuclear ribonucleoprotein assembly ⓘ small nucleolar RNP biogenesis ⓘ snRNP biogenesis ⓘ snRNP maturation ⓘ spliceosome assembly ⓘ telomerase RNP biogenesis ⓘ |
| locatedIn |
cell nucleus
ⓘ
nucleoplasm ⓘ |
| namedAfter | Santiago Ramón y Cajal NERFINISHED ⓘ |
| numberDependsOn |
cell cycle stage
ⓘ
transcriptional activity ⓘ |
| playsRoleIn |
RNP quality control
ⓘ
snRNA 2'-O-methylation ⓘ snRNA modification ⓘ snRNA pseudouridylation ⓘ |
| reassemblesDuring | G1 phase ⓘ |
| subclassOf | nuclear body ⓘ |
| visualizedBy |
electron microscopy
ⓘ
immunofluorescence microscopy ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Cajal bodies Description of subject: Cajal bodies are dynamic nuclear suborganelles involved in the biogenesis and maturation of small nuclear ribonucleoproteins (snRNPs) and other RNA-processing factors.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject surface form:
Survival motor neuron protein