Irwin Rose
E516461
Irwin Rose was an American biochemist and Nobel Prize laureate recognized for his pioneering work on the ubiquitin-mediated protein degradation pathway.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Irwin Rose canonical | 4 |
How this entity was disambiguated
This entity first appeared as the object of triple T5382882 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Irwin Rose Context triple: [Irwin, hasNotableBearer, Irwin Rose]
-
A.
Mark Ptashne
Mark Ptashne is an American molecular biologist renowned for his pioneering work on gene regulation and the discovery of how transcription factors control gene expression in phage and eukaryotic systems.
-
B.
Richard Losick
Richard Losick is an American molecular biologist renowned for his research on bacterial development and gene regulation, particularly in Bacillus subtilis.
-
C.
Phillip A. Sharp
Phillip A. Sharp is an American molecular biologist and Nobel laureate renowned for his discovery of RNA splicing and his long-standing research and leadership at MIT.
-
D.
Joan A. Steitz
Joan A. Steitz is an American molecular biologist renowned for her pioneering work on RNA biology and the discovery of small nuclear ribonucleoproteins (snRNPs) involved in RNA splicing.
-
E.
Harvey Shine
Harvey Shine is the middle-aged, down-on-his-luck jingle writer portrayed by Dustin Hoffman in the romantic drama film "Last Chance Harvey."
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Irwin Rose Target entity description: Irwin Rose was an American biochemist and Nobel Prize laureate recognized for his pioneering work on the ubiquitin-mediated protein degradation pathway.
-
A.
Mark Ptashne
Mark Ptashne is an American molecular biologist renowned for his pioneering work on gene regulation and the discovery of how transcription factors control gene expression in phage and eukaryotic systems.
-
B.
Richard Losick
Richard Losick is an American molecular biologist renowned for his research on bacterial development and gene regulation, particularly in Bacillus subtilis.
-
C.
Phillip A. Sharp
Phillip A. Sharp is an American molecular biologist and Nobel laureate renowned for his discovery of RNA splicing and his long-standing research and leadership at MIT.
-
D.
Joan A. Steitz
Joan A. Steitz is an American molecular biologist renowned for her pioneering work on RNA biology and the discovery of small nuclear ribonucleoproteins (snRNPs) involved in RNA splicing.
-
E.
Harvey Shine
Harvey Shine is the middle-aged, down-on-his-luck jingle writer portrayed by Dustin Hoffman in the romantic drama film "Last Chance Harvey."
- F. None of above. chosen
Statements (43)
| Predicate | Object |
|---|---|
| instanceOf |
Nobel laureate
ⓘ
biochemist ⓘ human ⓘ |
| academicDegree | PhD in biochemistry ⓘ |
| awardReceived |
Albert Lasker Award for Basic Medical Research
NERFINISHED
ⓘ
Nobel Prize in Chemistry NERFINISHED ⓘ |
| causeOfDeath | heart failure ⓘ |
| conflictParticipatedIn | World War II ⓘ |
| countryOfCitizenship | United States of America ⓘ |
| dateOfBirth | 1926-07-16 ⓘ |
| dateOfDeath | 2015-06-02 ⓘ |
| doctoralAdvisor | Henry Lardy NERFINISHED ⓘ |
| educatedAt |
University of Chicago
ⓘ
Washington State University NERFINISHED ⓘ |
| employer |
Fox Chase Cancer Center
NERFINISHED
ⓘ
University of California, Irvine NERFINISHED ⓘ |
| ethnicGroup | Jewish American ⓘ |
| familyName | Rose NERFINISHED ⓘ |
| fieldOfWork |
biochemistry
ⓘ
molecular biology ⓘ protein degradation ⓘ ubiquitin pathway ⓘ |
| givenName | Irwin NERFINISHED ⓘ |
| languageSpoken | English ⓘ |
| memberOf | National Academy of Sciences ⓘ |
| militaryService | United States Navy ⓘ |
| nobelPrizeCategory | Chemistry NERFINISHED ⓘ |
| nobelPrizeYear | 2004 ⓘ |
| notableAchievement |
discovery of role of ubiquitin in protein degradation
ⓘ
elucidation of ATP-dependent protein degradation ⓘ |
| notableStudent | Avram Hershko NERFINISHED ⓘ |
| notableWork | ubiquitin-mediated protein degradation pathway ⓘ |
| occupation | biochemist ⓘ |
| placeOfBirth | Brooklyn, New York City NERFINISHED ⓘ |
| placeOfDeath | Deerfield, Massachusetts NERFINISHED ⓘ |
| religion | Judaism ⓘ |
| residence |
California, United States
ⓘ
surface form:
California
Pennsylvania NERFINISHED ⓘ |
| sexOrGender | male ⓘ |
| sharesNobelPrizeWith |
Aaron Ciechanover
NERFINISHED
ⓘ
Avram Hershko NERFINISHED ⓘ |
| workLocation |
Irvine, California
NERFINISHED
ⓘ
Philadelphia ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Irwin Rose Description of subject: Irwin Rose was an American biochemist and Nobel Prize laureate recognized for his pioneering work on the ubiquitin-mediated protein degradation pathway.
Referenced by (4)
Full triples — surface form annotated when it differs from this entity's canonical label.