respiratory syncytial virus (RSV)

E474952

human pathogen orthopneumovirus virus

Respiratory syncytial virus (RSV) is a common contagious virus that primarily infects the respiratory tract, especially in infants and older adults, and is a leading cause of bronchiolitis and pneumonia worldwide.

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Observed surface forms (1)

Surface form	Occurrences
respiratory syncytial virus	2

Statements (69)

Predicate	Object
instanceOf	human pathogen ⓘ orthopneumovirus ⓘ virus ⓘ
affectsAgeGroup	immunocompromised individuals ⓘ infants ⓘ older adults ⓘ young children ⓘ
associatedWithComplication	apnea in young infants ⓘ respiratory failure ⓘ wheezing ⓘ
associatedWithLongTermOutcome	increased risk of asthma ⓘ recurrent wheezing in childhood ⓘ
attachmentMediatedBy	G protein ⓘ
biosafetyLevel	2 ⓘ
causesDisease	acute respiratory infection ⓘ bronchiolitis ⓘ lower respiratory tract infection ⓘ pneumonia ⓘ upper respiratory tract infection ⓘ
diagnosedBy	RT-PCR ⓘ antigen detection tests ⓘ viral culture ⓘ
discoveredBy	Robert M. Chanock NERFINISHED ⓘ
discoveredIn	1956 ⓘ
entryMediatedBy	F protein NERFINISHED ⓘ
enveloped	true ⓘ
family	Pneumoviridae NERFINISHED ⓘ
genus	Orthopneumovirus NERFINISHED ⓘ
globalBurden	major cause of infant hospitalization worldwide ⓘ
hasGenomeStructure	nonsegmented genome ⓘ
hasGenomeType	negative-sense single-stranded RNA ⓘ
hasProphylaxis	nirsevimab NERFINISHED ⓘ palivizumab ⓘ
hasProtein	F protein ⓘ G protein ⓘ L protein ⓘ M protein ⓘ M2 protein NERFINISHED ⓘ N protein ⓘ P protein ⓘ SH protein ⓘ
hasSerotype	RSV A NERFINISHED ⓘ RSV B NERFINISHED ⓘ
hasVaccine	RSV prefusion F protein-based vaccines ⓘ
incubationPeriod	2 to 8 days ⓘ
isLeadingCauseOf	bronchiolitis in infants ⓘ pneumonia in infants ⓘ
majorHost	humans ⓘ
parentTaxon	Human orthopneumovirus NERFINISHED ⓘ
preventedBy	avoidance of close contact with infected individuals ⓘ hand hygiene ⓘ respiratory etiquette ⓘ
primaryInfectionSite	lower respiratory tract ⓘ upper respiratory tract ⓘ
routeOfEntry	conjunctival mucosa ⓘ nasal mucosa ⓘ
seasonality	early spring ⓘ winter ⓘ
shape	pleomorphic ⓘ
taxonRank	species ⓘ
transmissionRoute	direct contact with respiratory secretions ⓘ fomites ⓘ respiratory droplets ⓘ
treatment	mechanical ventilation in severe cases ⓘ oxygen therapy ⓘ supportive care ⓘ
vaccineTargetGroup	high-risk infants ⓘ older adults ⓘ pregnant women ⓘ

Referenced by (3)

Full triples — surface form annotated when it differs from this entity's canonical label.

MedImmune → researchArea → respiratory syncytial virus (RSV) ⓘ

human adenovirus serotype 26 (Ad26) → usedInVaccineAgainst → respiratory syncytial virus (RSV) ⓘ

subject surface form: human adenovirus serotype 26

this entity surface form: respiratory syncytial virus

Mononegavirales → notableHumanPathogensInclude → respiratory syncytial virus (RSV) ⓘ

this entity surface form: respiratory syncytial virus