wingless
E459334
wingless is a key developmental gene in Drosophila melanogaster that encodes a Wnt family signaling protein crucial for embryonic patterning and tissue formation.
Statements (47)
| Predicate | Object |
|---|---|
| instanceOf |
developmental gene
ⓘ
gene ⓘ segment polarity gene ⓘ |
| discoveredIn | Drosophila genetic screens for segment polarity mutants ⓘ |
| encodes |
Wnt family signaling protein
ⓘ
morphogen ⓘ secreted glycoprotein ⓘ |
| foundInTaxon | Drosophila melanogaster NERFINISHED ⓘ |
| hasBiologicalRole |
cell differentiation regulation
ⓘ
cell fate determination ⓘ cell proliferation regulation ⓘ organ development ⓘ pattern specification ⓘ tissue polarity establishment ⓘ |
| hasConservedRoleIn | metazoan development ⓘ |
| hasMolecularFunction |
morphogen activity
ⓘ
signaling receptor binding ⓘ |
| hasPathwayComponent |
Armadillo
ⓘ
Dishevelled ⓘ Frizzled receptor NERFINISHED ⓘ TCF transcription factor ⓘ |
| isSecreted | true ⓘ |
| locatedOnChromosome | Drosophila melanogaster chromosome 2 NERFINISHED ⓘ |
| mutantPhenotype |
embryonic lethality
ⓘ
loss of wing structures ⓘ segment polarity defects ⓘ |
| nameOrigin | wingless adult phenotype of mutants ⓘ |
| orthologOf | Wnt1 NERFINISHED ⓘ |
| participatesIn |
Wnt signaling pathway
ⓘ
anterior-posterior patterning ⓘ axis specification ⓘ canonical Wnt signaling pathway ⓘ dorsal-ventral patterning ⓘ embryonic patterning ⓘ imaginal disc development ⓘ neurogenesis ⓘ non-canonical Wnt signaling pathway ⓘ segment polarity pathway ⓘ tissue formation ⓘ wing imaginal disc patterning ⓘ |
| regulates |
cell adhesion
ⓘ
cytoskeletal organization ⓘ engrailed expression ⓘ homeotic gene expression ⓘ |
| signalType |
autocrine signal
ⓘ
paracrine signal ⓘ |
| symbol | wg ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.