Antennapedia complex
E459332
The Antennapedia complex is a cluster of homeotic genes in fruit flies that controls segment identity and the proper development of body structures along the anterior–posterior axis.
Statements (45)
| Predicate | Object |
|---|---|
| instanceOf |
Hox gene cluster
ⓘ
gene cluster ⓘ homeotic gene complex ⓘ |
| associatedWith | body plan organization in arthropods ⓘ |
| contrastsWith | Bithorax complex NERFINISHED ⓘ |
| controls | segment identity along the anterior–posterior axis in Drosophila ⓘ |
| discoveredIn | 1970s ⓘ |
| encodes | homeobox-containing transcription factors ⓘ |
| expressedDuring | Drosophila embryogenesis ⓘ |
| foundInTaxon |
Drosophila
NERFINISHED
ⓘ
Drosophila melanogaster NERFINISHED ⓘ |
| geneticLocusType | complex locus ⓘ |
| genomicOrganization | cluster of tightly linked homeotic genes ⓘ |
| hasBiologicalRole | specification of segmental identity ⓘ |
| hasEffectOn | morphology of appendages in Drosophila ⓘ |
| hasHistoricalSignificance | provided key evidence for the concept of homeotic genes ⓘ |
| hasMolecularFunction | DNA-binding transcription factor activity ⓘ |
| hasPart |
Antennapedia gene
NERFINISHED
ⓘ
Deformed gene ⓘ Sex combs reduced gene NERFINISHED ⓘ labial gene ⓘ proboscipedia gene ⓘ |
| hasResearchUse |
model for studying Hox gene function
ⓘ
model for studying segmental patterning ⓘ |
| hasSequenceFeature | homeobox domain in its genes ⓘ |
| involvedIn |
anterior–posterior axis specification
ⓘ
embryonic development ⓘ homeotic transformation of segments ⓘ pattern formation ⓘ |
| isSubclusterOf | Drosophila Hox gene system NERFINISHED ⓘ |
| locatedOn | Drosophila melanogaster chromosome 3R NERFINISHED ⓘ |
| mutationEffect | homeotic transformation of antennae into legs ⓘ |
| orthologousTo | vertebrate Hox gene clusters ⓘ |
| partOf | Hox complex of Drosophila melanogaster NERFINISHED ⓘ |
| regulates |
development of gnathal segments via Deformed
ⓘ
development of head and thorax structures ⓘ development of labial segment via labial gene ⓘ development of mouthparts via proboscipedia ⓘ development of sex comb structures via Sex combs reduced ⓘ development of thoracic leg-bearing segments via Antennapedia ⓘ development of thoracic segments ⓘ identity of head and anterior thoracic segments ⓘ segment-specific gene expression programs ⓘ |
| studiedIn |
developmental genetics
ⓘ
evolutionary developmental biology ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.