Purkinje fibers

E431116

Purkinje fibers are specialized cardiac muscle fibers that rapidly conduct electrical impulses through the ventricles, coordinating their synchronized contraction.

All labels observed (1)

Label Occurrences
Purkinje fibers canonical 1

How this entity was disambiguated

Statements (46)

Predicate Object
instanceOf cardiac muscle fiber
component of cardiac conduction system
specialized conducting fiber
associatedWith bundle branch block when conduction impaired
ventricular arrhythmias when abnormal
bloodSupplyFrom coronary arteries
clinicalRelevance site of origin for some idiopathic ventricular tachycardias
target of some antiarrhythmic drugs
connectedTo left bundle branch
right bundle branch
ventricular myocardium
developFrom cardiac muscle cells
discoveredBy Jan Evangelista Purkyně NERFINISHED
discoveryYear 1839
electrophysiologyProperty can exhibit automaticity under pathological conditions
fast response action potentials
high upstroke velocity of phase 0
function coordination of synchronized ventricular contraction
distribution of impulses from bundle branches to ventricular myocardium
rapid conduction of electrical impulses in ventricles
hasProperty abundant glycogen
few myofibrils
high conduction velocity
large diameter
pale cytoplasm
poor contractile function
rich in gap junctions
specialized for impulse conduction rather than contraction
histologyFeature larger than surrounding ventricular myocytes
located beneath endocardium
myofibrils concentrated at periphery of cell
innervatedBy autonomic nervous system indirectly via myocardium
locatedIn left ventricle
right ventricle
subendocardial region of ventricles
namedAfter Jan Evangelista Purkyně NERFINISHED
partOf heart
ventricular conduction system
receivesImpulseFrom atrioventricular bundle
bundle branches
roleIn QRS complex of electrocardiogram
synchronous ventricular depolarization
speciesPresentIn humans
mammals
stainCharacteristic PAS positive due to glycogen
transmitsImpulseTo ventricular muscle cells

How these facts were elicited

Referenced by (1)

Full triples — surface form annotated when it differs from this entity's canonical label.

Heart hasPart Purkinje fibers