pXO2

E271804

pXO2 is a virulence-associated plasmid of Bacillus anthracis that encodes genes essential for the bacterium’s protective capsule formation.

All labels observed (1)

Label Occurrences
pXO2 canonical 1

How this entity was disambiguated

Statements (40)

Predicate Object
instanceOf extrachromosomal DNA element
plasmid
virulence plasmid
absentFrom many attenuated Bacillus anthracis vaccine strains
associatedWith anthrax
evasion of host immune response
protective capsule formation
resistance to phagocytosis
carriedBy virulent Bacillus anthracis strains
coexistsWith pXO1 plasmid in fully virulent strains
contributesTo pathogenicity of Bacillus anthracis
discoveredIn 20th century
enables capsule formation in Bacillus anthracis
encodes capsule biosynthesis genes
genes required for poly-γ-D-glutamic acid capsule
regulatory proteins for capsule expression
foundInTaxon Bacillus anthracis
geneticMaterial double-stranded DNA
hasMolecularFunction genetic determinant of capsule synthesis
hasPart acpA gene
acpB gene
capA gene
capB gene
capC gene
capD gene
pagR-like regulatory genes
location cytoplasm of Bacillus anthracis
lossOf reduces virulence in animal models
results in acapsular phenotype
organismType non-living genetic element
partOf virulence plasmid system of Bacillus anthracis
regulates expression of capsule operon
requiredFor full virulence of Bacillus anthracis in mammals
roleIn virulence of Bacillus anthracis
studiedIn biodefense research
microbial genetics
taxonRank not applicable
transmittedBy bacterial cell division
usedIn anthrax pathogenesis research
vaccine strain characterization

How these facts were elicited

Referenced by (1)

Full triples — surface form annotated when it differs from this entity's canonical label.