Crohn’s disease

E242405

autoimmune-related disorder chronic disease gastrointestinal disease inflammatory bowel disease

Crohn’s disease is a chronic inflammatory bowel disease that causes inflammation of the digestive tract, leading to symptoms such as abdominal pain, diarrhea, weight loss, and fatigue.

Try in SPARQL Jump to: Surface forms Disambiguation Statements Elicitation Referenced by

All labels observed (2)

Label	Occurrences
Crohn’s disease canonical	3
Crohn's disease	2

How this entity was disambiguated

This entity first appeared as the object of triple T2190598 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.

NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07

Target entity: Crohn’s disease
Context triple: [Remicade, isUsedFor, Crohn’s disease]

A. Colon Classification
Colon Classification is a faceted library classification system developed by S. R. Ranganathan that organizes knowledge using a combination of basic subject categories and auxiliary facets.
B. Gerd
Gerd is a masculine given name of German origin, commonly used in German-speaking countries.
C. Gaulanitis
Gaulanitis was an ancient region east of the Sea of Galilee, historically associated with the Golan area and mentioned in classical and biblical sources.
D. Wegener's granulomatosis
Wegener's granulomatosis, now more commonly called granulomatosis with polyangiitis, is a rare autoimmune disease characterized by inflammation of blood vessels that can damage organs such as the lungs, kidneys, and upper respiratory tract.
E. CRP
CRP was the common abbreviation for the Committee to Re-elect the President, the fundraising organization for U.S. President Richard Nixon’s 1972 reelection campaign, later infamous for its role in the Watergate scandal.
F. None of above. chosen
G. Unsure - the case is ambiguous/there is not enough information to decide.

NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07

Target entity: Crohn’s disease
Target entity description: Crohn’s disease is a chronic inflammatory bowel disease that causes inflammation of the digestive tract, leading to symptoms such as abdominal pain, diarrhea, weight loss, and fatigue.

A. Colon Classification
Colon Classification is a faceted library classification system developed by S. R. Ranganathan that organizes knowledge using a combination of basic subject categories and auxiliary facets.
B. Gerd
Gerd is a masculine given name of German origin, commonly used in German-speaking countries.
C. Gaulanitis
Gaulanitis was an ancient region east of the Sea of Galilee, historically associated with the Golan area and mentioned in classical and biblical sources.
D. Wegener's granulomatosis
Wegener's granulomatosis, now more commonly called granulomatosis with polyangiitis, is a rare autoimmune disease characterized by inflammation of blood vessels that can damage organs such as the lungs, kidneys, and upper respiratory tract.
E. CRP
CRP was the common abbreviation for the Committee to Re-elect the President, the fundraising organization for U.S. President Richard Nixon’s 1972 reelection campaign, later infamous for its role in the Watergate scandal.
F. None of above. chosen

Statements (65)

Predicate	Object
instanceOf	autoimmune-related disorder ⓘ chronic disease ⓘ gastrointestinal disease ⓘ inflammatory bowel disease ⓘ
affectsOrgan	colon ⓘ ileum ⓘ large intestine ⓘ small intestine ⓘ
affectsRegion	any part of the gastrointestinal tract from mouth to anus ⓘ
affectsSystem	digestive system ⓘ
associatedWith	NOD2 gene variants ⓘ immune dysregulation ⓘ
commonSymptom	abdominal pain ⓘ chronic diarrhea ⓘ fatigue ⓘ fever ⓘ rectal bleeding ⓘ reduced appetite ⓘ weight loss ⓘ
course	chronic ⓘ relapsing-remitting ⓘ
diagnosticMethod	CT enterography ⓘ MR enterography ⓘ blood tests for inflammation markers ⓘ colonoscopy with biopsy ⓘ endoscopy ⓘ stool tests ⓘ
epidemiology	more common in North America and Europe ⓘ
etiology	multifactorial ⓘ
extraIntestinalManifestation	arthritis ⓘ erythema nodosum ⓘ primary sclerosing cholangitis ⓘ uveitis ⓘ
firstDescribed	1932 ⓘ
management	dietary modification ⓘ smoking cessation ⓘ
medicalSpecialty	gastroenterology ⓘ immunology ⓘ
namedAfter	Burrill Bernard Crohn ⓘ
pathologyFeature	cobblestone appearance of mucosa ⓘ noncaseating granulomas ⓘ skip lesions ⓘ transmural inflammation ⓘ
possibleComplication	abscesses ⓘ bowel obstruction ⓘ colon cancer ⓘ fistulas ⓘ intestinal strictures ⓘ malnutrition ⓘ perianal disease ⓘ
prognosis	often requires lifelong management ⓘ variable ⓘ
riskFactor	Ashkenazi Jewish ancestry ⓘ Western diet ⓘ cigarette smoking ⓘ family history of inflammatory bowel disease ⓘ urban living ⓘ
treatment	TNF inhibitors ⓘ aminosalicylates ⓘ biologic therapies ⓘ corticosteroids ⓘ immunomodulators ⓘ surgical resection of affected bowel segments ⓘ
typicalOnset	adolescence ⓘ early adulthood ⓘ

How these facts were elicited

Referenced by (5)

Full triples — surface form annotated when it differs from this entity's canonical label.

Remicade → isUsedFor → Crohn’s disease ⓘ

Stelara → isUsedFor → Crohn’s disease ⓘ

David Garrard → diagnosedWith → Crohn’s disease ⓘ

this entity surface form: Crohn's disease

Anastacia → hasHealthCondition → Crohn’s disease ⓘ

Mike McCready → hasMedicalCondition → Crohn’s disease ⓘ