Cynthia Kenyon
E184182
Cynthia Kenyon is an American molecular biologist renowned for her pioneering research on the genetic regulation of aging and lifespan in the nematode C. elegans.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Cynthia Kenyon canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T1633913 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Cynthia Kenyon Context triple: [Calico LLC, keyPerson, Cynthia Kenyon]
-
A.
Virginia Katherine McMath
Virginia Katherine McMath, better known as Ginger Rogers, was an American actress, singer, and dancer famed for her iconic film musicals with Fred Astaire during Hollywood’s Golden Age.
-
B.
Linda Arvidson
Linda Arvidson was an early American silent film actress and writer, best known for her work in pioneering films of the 1900s and her association with director D. W. Griffith.
-
C.
Joan E. Donoghue
Joan E. Donoghue is an American jurist and former judge of the International Court of Justice who served as its president, becoming one of the most prominent contemporary figures in international law.
-
D.
Linda Salzman Sagan
Linda Salzman Sagan is an American artist and writer best known for co-designing the Pioneer plaque and contributing to other interstellar message projects alongside Carl Sagan.
-
E.
Jane Belson
Jane Belson was a British barrister best known as the wife of author Douglas Adams.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Cynthia Kenyon Target entity description: Cynthia Kenyon is an American molecular biologist renowned for her pioneering research on the genetic regulation of aging and lifespan in the nematode C. elegans.
-
A.
Virginia Katherine McMath
Virginia Katherine McMath, better known as Ginger Rogers, was an American actress, singer, and dancer famed for her iconic film musicals with Fred Astaire during Hollywood’s Golden Age.
-
B.
Linda Arvidson
Linda Arvidson was an early American silent film actress and writer, best known for her work in pioneering films of the 1900s and her association with director D. W. Griffith.
-
C.
Joan E. Donoghue
Joan E. Donoghue is an American jurist and former judge of the International Court of Justice who served as its president, becoming one of the most prominent contemporary figures in international law.
-
D.
Linda Salzman Sagan
Linda Salzman Sagan is an American artist and writer best known for co-designing the Pioneer plaque and contributing to other interstellar message projects alongside Carl Sagan.
-
E.
Jane Belson
Jane Belson was a British barrister best known as the wife of author Douglas Adams.
- F. None of above. chosen
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
American
ⓘ
academic ⓘ molecular biologist ⓘ scientist ⓘ |
| academicDegree |
Bachelor’s degree from the University of Georgia
ⓘ
PhD in biology from MIT ⓘ |
| awardReceived |
Fellow of the American Association for the Advancement of Science
ⓘ
surface form:
American Association for the Advancement of Science fellowship
Association of American Medical Colleges Award for Distinguished Research in the Biomedical Sciences ⓘ Ilse & Helmut Wachter Award ⓘ King Faisal International Prize ⓘ
surface form:
King Faisal International Prize for Medicine
|
| citizenship | United States of America ⓘ |
| doctoralAdvisor | Graham C. Walker ⓘ |
| educatedAt |
Massachusetts Institute of Technology
ⓘ
University of Georgia ⓘ |
| employer |
Calico
ⓘ
University of California, San Francisco ⓘ |
| fieldOfWork |
aging research
ⓘ
developmental biology ⓘ genetics ⓘ gerontology ⓘ molecular biology ⓘ |
| gender | female ⓘ |
| hasResearchFocus |
longevity pathways conserved across species
ⓘ
molecular mechanisms of aging ⓘ |
| influenced |
development of modern longevity research
ⓘ
research on dietary restriction and lifespan ⓘ |
| influencedBy | Sydney Brenner ⓘ |
| knownFor |
demonstrating that the daf-2 gene mutation can double the lifespan of C. elegans
ⓘ
discovering that single-gene mutations can dramatically extend lifespan in C. elegans ⓘ research on FOXO transcription factor daf-16 in C. elegans longevity ⓘ research on insulin/IGF-1 signaling pathway and lifespan ⓘ showing that aging is subject to genetic regulation ⓘ |
| languageSpoken | English ⓘ |
| memberOf |
American Academy of Arts and Sciences
ⓘ
National Academy of Sciences ⓘ
surface form:
National Academy of Sciences of the United States of America
|
| nationality | United States of America ⓘ |
| notableStudent | Andrew Dillin ⓘ |
| notableWork | 1993 Nature paper showing lifespan extension in C. elegans via daf-2 mutation ⓘ |
| positionHeld |
Herbert Boyer Distinguished Professor of Biochemistry and Biophysics at UCSF
ⓘ
Professor at University of California, San Francisco ⓘ Vice President of Aging Research at Calico ⓘ |
| postdoctoralAdvisor | Sydney Brenner ⓘ |
| researchSubject |
Caenorhabditis elegans
ⓘ
daf-16 gene ⓘ daf-2 gene ⓘ genetic regulation of lifespan ⓘ insulin/IGF-1 signaling pathway ⓘ |
| workInstitution | University of California, San Francisco ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Cynthia Kenyon Description of subject: Cynthia Kenyon is an American molecular biologist renowned for her pioneering research on the genetic regulation of aging and lifespan in the nematode C. elegans.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.