indoleamine 2,3-dioxygenase 1

E1160708 UNEXPLORED

Indoleamine 2,3-dioxygenase 1 is an immune-regulatory enzyme that catalyzes the initial oxidative degradation of tryptophan along the kynurenine pathway, influencing inflammation, tolerance, and tumor immune evasion.

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kynurenine pathway rateLimitingEnzyme indoleamine 2,3-dioxygenase 1