MRC Protein Phosphorylation and Ubiquitylation Unit
E104236
The MRC Protein Phosphorylation and Ubiquitylation Unit is a leading biomedical research center focused on understanding how protein phosphorylation and ubiquitylation regulate cellular processes and contribute to human disease.
All labels observed (1)
| Label | Occurrences |
|---|---|
| MRC Protein Phosphorylation and Ubiquitylation Unit canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T884789 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: MRC Protein Phosphorylation and Ubiquitylation Unit Context triple: [University of Dundee, operatesResearchCentre, MRC Protein Phosphorylation and Ubiquitylation Unit]
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A.
MRC LMB
MRC LMB is a world-renowned research institute in Cambridge, UK, known for pioneering work in molecular biology and numerous Nobel Prize–winning discoveries.
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B.
Babraham Research Campus
Babraham Research Campus is a major life sciences research and innovation hub near Cambridge, England, focused on bioscience, biotechnology, and academic–industry collaboration.
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C.
Wellcome–MRC Institute of Metabolic Science
The Wellcome–MRC Institute of Metabolic Science is a leading research center at the University of Cambridge focused on understanding and treating metabolic diseases such as obesity and diabetes.
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D.
Cambridge Stem Cell Institute
The Cambridge Stem Cell Institute is a leading research center at the University of Cambridge dedicated to understanding stem cell biology and translating this knowledge into new treatments for human disease.
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E.
MRC Cognition and Brain Sciences Unit
The MRC Cognition and Brain Sciences Unit is a leading UK research institute in Cambridge focused on understanding human cognition and brain function through experimental and neuroimaging methods.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: MRC Protein Phosphorylation and Ubiquitylation Unit Target entity description: The MRC Protein Phosphorylation and Ubiquitylation Unit is a leading biomedical research center focused on understanding how protein phosphorylation and ubiquitylation regulate cellular processes and contribute to human disease.
-
A.
MRC LMB
MRC LMB is a world-renowned research institute in Cambridge, UK, known for pioneering work in molecular biology and numerous Nobel Prize–winning discoveries.
-
B.
Babraham Research Campus
Babraham Research Campus is a major life sciences research and innovation hub near Cambridge, England, focused on bioscience, biotechnology, and academic–industry collaboration.
-
C.
Wellcome–MRC Institute of Metabolic Science
The Wellcome–MRC Institute of Metabolic Science is a leading research center at the University of Cambridge focused on understanding and treating metabolic diseases such as obesity and diabetes.
-
D.
Cambridge Stem Cell Institute
The Cambridge Stem Cell Institute is a leading research center at the University of Cambridge dedicated to understanding stem cell biology and translating this knowledge into new treatments for human disease.
-
E.
MRC Cognition and Brain Sciences Unit
The MRC Cognition and Brain Sciences Unit is a leading UK research institute in Cambridge focused on understanding human cognition and brain function through experimental and neuroimaging methods.
- F. None of above. chosen
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
biomedical research institute
ⓘ
medical research organization ⓘ research unit ⓘ |
| contributesTo |
basic biomedical research
ⓘ
drug target discovery ⓘ translational research ⓘ |
| focusesOn |
cellular signaling pathways
ⓘ
molecular mechanisms of human disease ⓘ protein phosphorylation ⓘ protein ubiquitylation ⓘ regulation of cellular processes ⓘ |
| goal |
elucidate mechanisms underlying human disease
ⓘ
identify potential therapeutic targets ⓘ understand how protein phosphorylation regulates cell function ⓘ understand how protein ubiquitylation regulates cell function ⓘ |
| hasKeyword |
cell signaling
ⓘ
human disease mechanisms ⓘ phosphorylation ⓘ ubiquitylation ⓘ |
| regulates |
research on E3 ubiquitin ligases
ⓘ
research on deubiquitylating enzymes ⓘ research on protein kinases ⓘ |
| researchArea |
biochemistry
ⓘ
cell biology ⓘ kinase signaling ⓘ molecular biology ⓘ post-translational modifications ⓘ signal transduction ⓘ ubiquitin signaling ⓘ |
| studiesDisease |
cancer
ⓘ
inflammatory diseases ⓘ metabolic disorders ⓘ neurodegenerative diseases ⓘ rare genetic disorders affecting signaling pathways ⓘ |
| studiesProcess |
cell division
ⓘ
cell growth regulation ⓘ cell survival pathways ⓘ cellular stress responses ⓘ inflammatory signaling ⓘ metabolic regulation ⓘ protein degradation pathways ⓘ signal transduction cascades ⓘ ubiquitin–proteasome system ⓘ |
| usesMethod |
biochemical assays
ⓘ
cell-based assays ⓘ genetic approaches ⓘ molecular biology techniques ⓘ proteomics ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: MRC Protein Phosphorylation and Ubiquitylation Unit Description of subject: The MRC Protein Phosphorylation and Ubiquitylation Unit is a leading biomedical research center focused on understanding how protein phosphorylation and ubiquitylation regulate cellular processes and contribute to human disease.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.
University of Dundee
→
operatesResearchCentre
→
MRC Protein Phosphorylation and Ubiquitylation Unit
ⓘ