Plasmodium falciparum malaria

E1000769

infectious disease parasitic disease vector-borne disease

Plasmodium falciparum malaria is the most severe and deadly form of human malaria, caused by the protozoan parasite Plasmodium falciparum and transmitted by Anopheles mosquitoes.

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Observed surface forms (1)

Surface form	Occurrences
Plasmodium falciparum	1

Statements (72)

Predicate	Object
instanceOf	infectious disease ⓘ parasitic disease ⓘ vector-borne disease ⓘ
affects	humans ⓘ liver ⓘ red blood cells ⓘ
belongsToCategory	falciparum malaria ⓘ
cause	acute kidney injury ⓘ anemia ⓘ cerebral malaria ⓘ chills ⓘ complicated malaria ⓘ fever ⓘ headache ⓘ high parasitemia ⓘ hypoglycemia ⓘ jaundice ⓘ metabolic acidosis ⓘ multi-organ failure ⓘ pulmonary edema ⓘ severe anemia ⓘ severe malaria ⓘ shock ⓘ
differsFrom	Plasmodium knowlesi malaria NERFINISHED ⓘ Plasmodium malariae malaria ⓘ Plasmodium ovale malaria ⓘ Plasmodium vivax malaria ⓘ
geographicDistribution	Oceania NERFINISHED ⓘ South Asia NERFINISHED ⓘ Southeast Asia NERFINISHED ⓘ parts of Latin America ⓘ sub-Saharan Africa NERFINISHED ⓘ
hasCausativeAgent	Plasmodium falciparum NERFINISHED ⓘ
hasComplication	cerebral malaria ⓘ low birth weight ⓘ maternal anemia ⓘ placental malaria ⓘ stillbirth ⓘ
hasHighestBurdenIn	sub-Saharan Africa NERFINISHED ⓘ
hasIncubationPeriod	approximately 7 to 14 days ⓘ
hasLifeCycleStage	blood stage ⓘ gametocyte stage ⓘ liver stage ⓘ
hasPathogenesisFeature	cytoadherence of infected erythrocytes ⓘ endothelial activation ⓘ rosetting of red blood cells ⓘ sequestration in microvasculature ⓘ
hasRiskFactor	HIV infection ⓘ lack of immunity ⓘ pregnancy ⓘ residence in endemic area ⓘ young age ⓘ
intermediateHost	Anopheles mosquito NERFINISHED ⓘ
isLeadingCauseOf	malaria-related mortality worldwide ⓘ
preventedBy	chemoprophylaxis ⓘ indoor residual spraying ⓘ insecticide-treated bed nets ⓘ intermittent preventive treatment in pregnancy ⓘ
primaryHost	human ⓘ
recognizedBy	World Health Organization NERFINISHED ⓘ
transmissionRoute	blood transfusion ⓘ congenital transmission ⓘ mosquito bite ⓘ
transmittedBy	Anopheles funestus NERFINISHED ⓘ Anopheles gambiae complex NERFINISHED ⓘ Anopheles mosquito NERFINISHED ⓘ
treatedWith	artemisinin-based combination therapy ⓘ atovaquone-proguanil ⓘ intravenous artesunate ⓘ mefloquine ⓘ quinine ⓘ
vector	female Anopheles mosquito ⓘ

Referenced by (2)

Full triples — surface form annotated when it differs from this entity's canonical label.

Pontine Marshes → notableDisease → Plasmodium falciparum malaria ⓘ

Anopheles mosquitoes → vectorFor → Plasmodium falciparum malaria ⓘ

subject surface form: Anopheles

this entity surface form: Plasmodium falciparum